Relationship Between Liver Cancer and Sarcopenia

The Effect of Sarcopenia on Hepatocellular Carcinoma After Hepatectomy

By tracking the short-term and long-term results of patients after hepatectomy, the difference of short-term results between patients with sarcopenia and patients without sarcopenia was analyzed, and the correlation between sarcopenia and short-term and long-term results of patients after hepatectomy was explored, so as to improve people's awareness of sarcopenia and pay attention to its prevention and treatment.

All implementation details are based on the newest EWGSOP definition. The investigators consecutively admitted patients the questionnaire and evaluated the assessment of muscle strength (grip strength test and chair stand test), muscle quantity (L3 plane total skeletal muscle area) and physical performance (gait test) following the F-A-C-S approach, to confirm patients with sarcopenia accurately. And by tracking the short-term and long-term outcomes of patients after hepatectomy, the differences were analyzed and the relationship between sarcopenia and liver cancer was explored.

Inclusion Criteria:

• Patients with preoperative clinical diagnosis of liver cancer
• No cancer other than liver cancer has been diagnosed
• Age ≥18 years

Exclusion Criteria:

• Patients who could not complete the standard tests and questionnaires
• Patients who did not accept liver resection after evaluation of treatment plan
• Patients who had other concomitant preoperative causes of muscle weakness (injury, fracture, stroke, etc.)
• Patients who missing CT data or CT scan did not reach the level of the third lumbar vertebra (L3)