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Post partum haemorrhage is a concerning situation in maternity wards, though it is not the first cause of maternal mortality anymore.
It has been already shown that low fibrinogen level is a major predictive factor of massive bleeding after delivery.
In this situation, the early knowledge of fibrinogen level could enhance care of women experiencing post partum haemorrhage.
In a cohort of women suffering from post partum haemorrhage, this study will evaluate whether assessing fibrinogen level would be faster using the Quantra® system than the standard coagulation test.
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| Measure | Description | Time Frame |
|---|---|---|
| Comparison of delay in obtaining Quantra Fibrinogen Clot Stiffness result to standard fibrinogen level result | Comparison of delay in obtaining Quantra Fibrinogen Clot Stiffness result to standard fibrinogen level result | When post partum haemorrhage occurred, within 24 hours after delivery |
| Measure | Description | Time Frame |
|---|---|---|
| Comparison of level of fibrinogen assessed by Quantra Fibrinogen Clot Stiffness to level of fibrinogen assessed by standard coagulation test | Fibrinogen level assessed by Quantra and standard coagulation tests | When post partum haemorrhage occurred, within 24 hours after delivery |
| Comparison of Quantra Clot Time result to Standard Kaolin Clotting time result |
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Inclusion Criteria:
Women ≥ 18 years old Experiencing post partum haemorrhage ≥ 500 mL Within 24 hours after delivery
Exclusion Criteria:
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Women ≥ 18 years old experiencing post partum haemorrhage ≥ 500 mL
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Jessie Grenié, MD | Contact | 00330467336472 | j-grenie@chu-montpellier.fr |
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| ID | Term |
|---|---|
| D006473 | Postpartum Hemorrhage |
| D006470 | Hemorrhage |
| ID | Term |
|---|---|
| D007744 | Obstetric Labor Complications |
| D011248 | Pregnancy Complications |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
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Coagulation function assessed by Quantra and standard coagulation tests |
| When post partum haemorrhage occurred, within 24 hours after delivery |
| Comparison of Platelet Clot Stiffness result to standard platelet count result | Platelet function assessed by Quantra and standard platelet count. | When post partum haemorrhage occurred, within 24 hours after delivery |
| Rate of satisfaction of anesthetist in charge of patient assessed by Lickert scale | Rate of satisfaction of anesthetist in charge of patient assessed by Lickert scale [1-Strongly disagree ; 2-Disagree ; 3-Neither agree nor disagree ; 4-Agree ; 5-Strongly agree](streamdown:incomplete-link) | When post partum haemorrhage occurred, within 24 hours after delivery |
| D011644 | Puerperal Disorders |
| D014592 | Uterine Hemorrhage |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |