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| ID | Type | Description | Link |
|---|---|---|---|
| 2020-A03000-39 | Other Identifier | ID-RCB number,ANSM |
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Postpartum hemorrhage (PPH) remains the leading cause of maternal death. PPH associated coagulopathy varies and their treatments (tranexamic acid, fibrinogen concentrates,plasma, platelets need to be targeted and administrated early. Point of care hemostasis devices are helpful to develop this strategy. Quantra® (STAGO BIOCARE) use an innovative method to detect the clot formation. Pregnancy and non-hemorrhagic postpartum reference ranges are missing. The objective of this study is to establish these norms needed to elaborate thereafter the thresholds to be targeted in PPH conditions.
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| Measure | Description | Time Frame |
|---|---|---|
| Description of the QUANTRA® parameters range intervals before and after vaginal delivery | At admission (= before delivery ) | |
| Description of the QUANTRA® parameters range intervals before and after vaginal delivery | At 30 minutes +/- 10 minutes after delivery |
| Measure | Description | Time Frame |
|---|---|---|
| Description of the QUANTRA® parameters range intervals before and after vaginal delivery | At 30 up to 60 minutes after birth and placental removal. | |
| Comparison between end of pregnancy and immediate postpartum reference values (both vaginal and caesarean deliveries) |
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Inclusion Criteria:
Exclusion Criteria:
pregnant women
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a cohort of Healthy pregnant woman (indemne of any chronic pathology neither obstetrical pathology)
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| Name | Affiliation | Role |
|---|---|---|
| Anne-Sophie DUCLOY-BOUTHORS, MD | University Hospital, Lille | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hop Jeanne de Flandre Chu Lille | Lille | 59037 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 40252700 | Result | Lukowiak O, Le Gouez A, Djebbour M, Mercier FJ, Bouthors AS. Peri-partum reference range for the point-of-care viscoelastic testing device Quantra(R) QStat in healthy pregnancy and non-haemorrhagic post-partum - A short communication. Anaesth Crit Care Pain Med. 2025 Aug;44(4):101521. doi: 10.1016/j.accpm.2025.101521. Epub 2025 Apr 17. |
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| ID | Term |
|---|---|
| D020141 | Hemostatic Disorders |
| ID | Term |
|---|---|
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D006474 | Hemorrhagic Disorders |
| D006402 | Hematologic Diseases |
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| At 30 up to 60 minutes after birth |
| D006425 |
| Hemic and Lymphatic Diseases |