Effect of Glycopyrronium in Combination With Tropisetron in Anti-postoperative Nausea and Vomiting

Effect of Glycopyrronium in Combination With Tropisetron in Anti-postoperative Nausea and Vomiting

To compare the anti-nausea and vomiting effect between glycopyrronium in combination with tropisetron and normal saline in combination with tropisetron for patients receiving elective surgery under general anesthesia. Based on this study the investigators intend to explore the feasibility of using glycopyrronium as adjuvant drug to prevent postoperative nausea and vomiting.

Inclusion Criteria:

• Non-cardiac surgery
• American Society of Anesthesiologists classification I-III
• Receive general anesthesia
• Voluntarily receive postoperative intravenous controlled analgesia

Exclusion Criteria:

• Puerpera or lactation women
• Allergy or existing contraindication to glycopyrronium and tropisetron
• Participate in other clinical drug trials within three months
• Can not follow with the study procedure