Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
In this study, the investigators compared the improvement of liver reserve function related indicators in patients with liver cirrhosis after laparoscopic splenectomy. To determine whether surgical treatment can help enhance postoperative liver reserve function and improve patient prognosis.
The patients were enrolled according to the research criteria, and collected the general basic information of the patients. After the preoperative preparation was perfected, the same surgical team performed laparoscopic splenectomy, and the same nursing team performed the nursing after the operation. Then, patients received a unified treatment plan after surgery, including medication, other treatments and follow-up. During the treatment, the liver reserve function related indicators of the patients were monitored before surgery, 3, 6, 12 and 24 months after surgery, including TBIL, DBIL, ALB, ALT, INR, PT, Child-Pugh, ascites, prealbumin, ICG-K, ICG-R 15 and ICG-T/2.
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Experimental Group | Other | Laparoscopic splenectomy |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Laparoscopic splenectomy | Procedure | The laparoscopic splenectomy was performed by the same surgical team. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Liver reserve function ICG-K level at 3 months after surgery | The level of liver reserve function ICG-K level at 3 months after surgery. | 3 months |
| Liver reserve function ICG-K level at 6 months after surgery. | The level of liver reserve function ICG-K level at 6 months after surgery. | 6 months |
| Liver reserve function ICG-K level at 12 months after surgery | The level of liver reserve function ICG-K level at 12 months after surgery. | 12 months |
| Liver reserve function ICG-K level at 24 months after surgery. | The level of liver reserve function ICG-K level at 24 months after surgery. | 24 months |
| Liver reserve function ICG-R15 level at 3 months after surgery. | The level of liver reserve function ICG-R15 level at 3 months after surgery. | 3 months |
| Liver reserve function ICG-R15 level at 6 months after surgery. | The level of liver reserve function ICG-R15 level at 6 months after surgery. | 6 months |
| Liver reserve function ICG-R15 level at 12 months after surgery. | The level of liver reserve function ICG-R15 level at 12 months after surgery. | 12 months |
Not provided
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Guo-Qing Jiang, MD | Contact | +8651487373272 | jgqing2003@hotmail.com | |
| Dou-Sheng Bai, MD | Contact | +8651487373372 | bdsno1@hotmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Guo-Qing Jiang, MD | Clinical Medical College of Yangzhou University | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Clinical Medical College of Yangzhou University | Recruiting | Yangzhou | Jiangsu | 225001 | China |
Not provided
| ID | Term |
|---|---|
| D008103 | Liver Cirrhosis |
| D005355 | Fibrosis |
| ID | Term |
|---|---|
| D008107 | Liver Diseases |
| D004066 | Digestive System Diseases |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Liver reserve function ICG-R15 level at 24 months after surgery. |
The level of liver reserve function ICG-R15 level at 24 months after surgery. |
| 24 months |
| Liver reserve function ICG-T/2 level at 3 months after surgery. | The level of liver reserve function ICG-T/2 level at 3 months after surgery. | 3 months |
| Liver reserve function ICG-T/2 level at 6 months after surgery. | The level of liver reserve function ICG-T/2 level at 6 months after surgery. | 6 months |
| Liver reserve function ICG-T/2 level at 12 months after surgery. | The level of liver reserve function ICG-T/2 level at 12 months after surgery. | 12 months |
| Liver reserve function ICG-T/2 level at 24 months after surgery. | The level of liver reserve function ICG-T/2 level at 24 months after surgery. | 24 months |