GLUCOSAMINE/CHONDROITIN and PHYSICAL THERAPY EFFECTS ON OLDER POPULATION WITH KNEE OSTEOARTHRITIS

EFFECTS OF COMBINED GLUCOSAMINE/CHONDROITIN WITH STRUCTURED PHYSICAL THERAPY PROGRAM ON KNEE OSTEOARTHRITIS: A RANDOMIZED CONTROL TRAIL

to see the effect of glucosamine chondratin sulfate with and without physiotherapy in knee osteoarthritis

it is a randomized control trail to evaluate the effectiveness of glucosamine chondratin sulfate alone and in combination with physiotherapy on knee osteoarthritis

Inclusion Criteria:

• age > 50 years with radiographic evidence of mild to moderate knee OA (Kellgren Lawrence grade II & III 20) who met the ACR clinical 21,
• radiographic classification criteria or confirmation of mild to moderate radiographic evidence of knee OA from a personal physician
• not currently participating in another intervention study

Exclusion Criteria:

• dementia (Mini-Mental State Examination [MMSE]< 24)
• active cancer other than skin cancer
• anemia (participants with an hematocrit (HCT)< 32 (or a hemoglobin below10) were excluded due to possible inability to adequately exercise or the increased potential for increased risk for serious adverse cardiovascular events)
• severe renal insufficiency (serum creat> 2)
• hepatic disease