Effect of Barley Supplemented Wheat Bread on Markers of Cardiovascular and Renal Health

Effect of Barley Supplemented Wheat Bread on Markers of Cardiovascular and Renal Health: A Randomized Controlled Trial

The disruption of colonic microbiota has been linked to a number of diseases, mainly cardiovascular and kidney diseases. One possible means to improve the microbiota is to increase dietary fiber intake as the intake of dietary fiber shifts the fermentation from proteolytic saccharolytic fermentation.

Beta-glucans are soluble dietary fibers mainly found in oats and barley. Results from previous studies suggest that the consumption of barley reduces the risk of cardiovascular and kidney diseases. Therefore, this study will explore the effect of barley beta-glucans on markers of Cardiovascular and Renal health.

Inclusion Criteria:

• Healthy individuals of age 18 years or older
• BMI ranged between 18.5 and 24.9

Exclusion Criteria:

• Celiac disease, Cancer, Diabetes , cardiovascular diseases
• Gastro intestinal tract disease
• Pregnant women
• Use of pre-, pro- or antibiotics 15 days before the enrollment into the study
• Food allergy to food used in the trial