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Anemia is common in patients on hemodialysis (HD) due to lack of erythropoietin (EPO) synthesis and iron deficiency is occurring in HD patients due to chronic blood loss through the dialysis circuit, repeated blood sampling, shortened red blood cell life span and lack of adherence to treatment .
Anemia is one of the most important complications that affects morbidity and mortality in chronic kidney disease (CKD) patients. It has significant impacts on those patients such as fatigue, weakness, shortness of breath, decreased quality of life, exercise capacity and physical activity, growth retardation and decreased cognitive functions, left ventricular hypertrophy, and congestive heart failure So, proper management of anemia is very important .
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| responsiveness to erythropoietin stimulating agent | we evolute responsiveness of patients on hemodialysis for erythropoietin stimulating agents or not and factors effecting this response |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| seum zinic,vit B12, parathyriod function | Diagnostic Test | seum zinic,vit B12, parathyriod function |
|
| Measure | Description | Time Frame |
|---|---|---|
| Hb g/dl | measure hemoglobin level | one year |
| Iron profile | measure iron profile on blood | one year |
| Serum creatinine | serum creatinine | one year |
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Inclusion Criteria:
Exclusion Criteria:
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These children are attending in our Pediatric dialysis unit at Sohag University Hospital, Egypt between April 2022 and April 2023.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| hanan N fawzi, specialist | Contact | 01009351849 | hanan_nagdy_post@med.sohag.edu.eg | |
| Alzahraa A Ahmed, professor | Contact |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Sohag University Hospital | Sohag | Egypt |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 29023171 | Background | Allali S, Brousse V, Sacri AS, Chalumeau M, de Montalembert M. Anemia in children: prevalence, causes, diagnostic work-up, and long-term consequences. Expert Rev Hematol. 2017 Nov;10(11):1023-1028. doi: 10.1080/17474086.2017.1354696. Epub 2017 Oct 12. | |
| 29191165 | Background | Mikhail A, Brown C, Williams JA, Mathrani V, Shrivastava R, Evans J, Isaac H, Bhandari S. Renal association clinical practice guideline on Anaemia of Chronic Kidney Disease. BMC Nephrol. 2017 Nov 30;18(1):345. doi: 10.1186/s12882-017-0688-1. |
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| Type | Date | Date Unknown |
|---|---|---|
| Release | Jul 7, 2024 | |
| Reset | Oct 11, 2024 |
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| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Jul 7, 2024 | Oct 11, 2024 |
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| 21697809 | Background | Bamgbola OF. Pattern of resistance to erythropoietin-stimulating agents in chronic kidney disease. Kidney Int. 2011 Sep;80(5):464-74. doi: 10.1038/ki.2011.179. Epub 2011 Jun 22. |
| 25511161 | Background | Akbari A, Clase CM, Acott P, Battistella M, Bello A, Feltmate P, Grill A, Karsanji M, Komenda P, Madore F, Manns BJ, Mahdavi S, Mustafa RA, Smyth A, Welcher ES. Canadian Society of Nephrology commentary on the KDIGO clinical practice guideline for CKD evaluation and management. Am J Kidney Dis. 2015 Feb;65(2):177-205. doi: 10.1053/j.ajkd.2014.10.013. Epub 2014 Nov 4. |