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Burning mouth syndrome is an idiopathic condition characterized by symptoms burning and / or pain of the oral mucosa with an orderly clinical finding. So far not found a unique way of treatment. It is a diagnosis that impairs the quality of life of patients, and consequently it can affect the quality of sleep. Melatonin is a hormone secreted from pineal gland and regulates the day-night rhythm of man, and whose production in the body decreases aging. The level of melatonin in saliva correlates well with the level of melatonin in plasma, therefore they are advantages of determining from saliva painlessness and non-invasiveness of the procedure itself. The purpose of this study was to compare the level of melatonin in saliva and the quality of sleep with help of the Epworth Sleepiness Scale in patients with burning mouth syndrome and control groups of patients without subjective oral disorders and with an orderly clinical finding.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Study group | Female patients of the Department of Oral medicine diagnosed with burning mouth syndrome |
| |
| Control group | Age-matched female patients without oral lesions and without burning mouth syndrome |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Epworth's sleepiness scale; unstimulated saliva sample | Other | Unstimulated saliva sample; Epworth's sleepiness scale |
|
| Measure | Description | Time Frame |
|---|---|---|
| determining the level of salivary melatonin | The level of salivary melatonin will be determined in frozen samples of unstimulated saliva samples | January 2021-July 2021 |
| Measure | Description | Time Frame |
|---|---|---|
| determining the difference in Epworth's sleepiness scale | The test is a list of eight situations in which you rate your tendency to become sleepy on a scale of 0, no chance of dozing, to 3, high chance of dozing. Total score is graded from 0-24. 0-7:It is unlikely that you are abnormally sleepy. 8-9:You have an average amount of daytime sleepiness. 10-15:You may be excessively sleepy depending on the situation. You may want to consider seeking medical attention. 16-24:You are excessively sleepy and should consider seeking medical attention. |
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Inclusion Criteria:
Exclusion Criteria:
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Female patients with burning mouth syndrome and age-matched female controls without burning mouth syndrome or oral lesions will be included in the study. A sample of unstimulated saliva will be taken from all patients and frozen. All patients will also fill in Epworth's sleepiness scale.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| School of Dental Medicine, University of Zagreb | Zagreb | 10000 | Croatia |
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| ID | Term |
|---|---|
| D002054 | Burning Mouth Syndrome |
| ID | Term |
|---|---|
| D009059 | Mouth Diseases |
| D009057 | Stomatognathic Diseases |
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unstimulated saliva samples
| January 2021-July 2021 |