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The aim of this study was to determine the level of salivary estradiol, progesterone and dehydroepiandrosterone in female postmenopausal women with and without burning mouth syndrome. In all participants the quantity of unstimulated and stimulated saliva would be determined and they would fulfill self-perceived quality of life questionnaire Oral Health Impact Profile-14 (OHIP-14). Intensity of burning symptoms would be determined on visual-analogue scale grading 0-10. All data would be compared between study and control group.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| study group | female postmenopausal women with burning mouth syndrome |
| |
| control group | female postmenopausal women without burning mouth syndrome |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| unstimulated saliva sample for hormone analysis | Diagnostic Test | hormone levels will be determined in frozen samples of unstimulated saliva |
|
| Measure | Description | Time Frame |
|---|---|---|
| to evaluate the levels of salivary hormone | levels of salivary 17β-Estradiol, progesterone and DHEA were determined in study and control group | November 2019-June 2020 |
| Measure | Description | Time Frame |
|---|---|---|
| to evaluate quality of life and correlate it with levels of salivary hormones and intensity of symptoms | quality of life was evaluated with self-perceived questionnaire OHIP-14 | November 2019-June 2020 |
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Inclusion Criteria:
Exclusion Criteria:
postmenopausal women
postmenopausal women are most frequently affected with burning mouth syndrome, and we wanted the groups to be as similar as possible so we included only postmenopausal women, with and without burning mouth syndrome
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| School of Dental Medicine, University of Zagreb | Zagreb | 10000 | Croatia |
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| quality of life questionnaire | Other | all participants will fill out self-perceived quality of life questionnaire |
|
| ID | Term |
|---|---|
| D002054 | Burning Mouth Syndrome |
| D004700 | Endocrine System Diseases |
| ID | Term |
|---|---|
| D009059 | Mouth Diseases |
| D009057 | Stomatognathic Diseases |
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