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Comparison of I/V nalbuphine versus I/V xylocain in attanuation of pressor response during intubation and laryngeoscopy in patients undergoing for thyroid surgery,selection of better supressor agent minimises the drug repated side effects like hypertention tachycardia but also helps in heamodynamically stability at induction.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Lignocain | Experimental | I/V lignocain 1.5mg per kg given to participants in state dose |
|
| nalbuphine | Experimental | I/v nalbuphine 0.1mg per kg given to participants in stat dose |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Lignocaine | Drug | Inj lignocain and inj nalbuphine given to two groups of participants and effects of both drugs |
|
| Measure | Description | Time Frame |
|---|---|---|
| Reduce stress response during intubation and hemodynamic stabilty | Assesment of Hemodynamic stability by observing vital signs | 10 minutes |
| Achieve hemodynamic stabilty and smooth intubation | Assesment of hemodynamic stability by clinical examination of vital signs | 10 minutes |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Dr.amna Sarwar, Fcps | Contact | 03218337129 | Dr.amnasabir@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Dr.amna Sarwar, Fcps | Sheikh zaied medical hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Dr.amna | Rahim Yar Khan | Punjab Province | 092 | Pakistan |
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| ID | Term |
|---|---|
| D008012 | Lidocaine |
| D009266 | Nalbuphine |
| ID | Term |
|---|---|
| D000083 | Acetanilides |
| D000813 | Anilides |
| D000577 | Amides |
| D009930 | Organic Chemicals |
| D000814 | Aniline Compounds |
| D000588 | Amines |
| D009019 | Morphinans |
| D053610 | Opiate Alkaloids |
| D000470 | Alkaloids |
| D006571 | Heterocyclic Compounds |
| D006572 | Heterocyclic Compounds, Bridged-Ring |
| D006576 | Heterocyclic Compounds, 4 or More Rings |
| D000072471 | Heterocyclic Compounds, Fused-Ring |
| D010616 | Phenanthrenes |
| D011084 | Polycyclic Aromatic Hydrocarbons |
| D011083 | Polycyclic Compounds |
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