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| ID | Type | Description | Link |
|---|---|---|---|
| 2021-A03064-37 | Other Identifier | ID-RCB number, ANSM |
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Single-center, prospective, controlled, parallel, randomized, single-blind study comparing the conventional extubation technique to two positive pressure extubation techniques on postoperative desaturations
Study realise on university hospital on Lille in France. Patients inclusion is prospective and randomised in three groups. First group : extubation is realised with aspiration in tracheal tube during removal tube Second group : extubation is realised without aspiration but with APL valve set to 20cmH20 Third group : extubation is realised without aspiration but with ventilator parameters were set for PSV mode (inspiratory pressure of 10cmH2O and PEEP identical to that administered in the operating room
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| control group | No Intervention | Classical extubation technique : ETT was removed with continuous endotracheal suction | |
| VSPEP | Experimental | ETT was removed with APL valve set to 20cmH2O |
|
| VSAIPEP | Experimental | ETT removed with ventilator parameters were set for PSV mode (inspiratory pressure of 10cmH2O and PEEP identical to that administered in the operating room |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| positive pressure during extubation procedure | Procedure | positive pressure during extubation procedure |
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| Measure | Description | Time Frame |
|---|---|---|
| desaturations during extubation | saturation <92% | 1 minute after extubation |
| Measure | Description | Time Frame |
|---|---|---|
| desaturation postoperatory | saturation<92% | 5 and 30 minutes after extubation |
| hypoxemia post operatory | PaO2 <60mmHg | 1 and 30 minutes after extubation |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Cédric CIRENEI, MD | University Hospital, Lille | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hop Claude Huriez Chu Lille | Lille | 59037 | France |
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| ID | Term |
|---|---|
| D011183 | Postoperative Complications |
| ID | Term |
|---|---|
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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Single-center, prospective, controlled, parallel, randomized, single-blind study comparing the conventional extubation technique to two positive pressure extubation techniques
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patients under anaesthesia at randomization
| atelectasis | Lung ultrasound score (LUS); min = 0, max = 32, higher scores mean is worse outcome | 30 minutes after extubation |
| awakening time | time in seconds | through extubation completion, an average 2 minutes |
| use of oxygen | days Numbers of oxygen therapy, kinesiotherapy, non invasive ventilation | day 7 |
| post operative complications | Clavien Dindo Score; min = grade I, max = grade V; higher scores mean is worse outcome | day 7 and day 28 |
| feasibility and acceptance of both techniques pressure positive extubation | questionnaire, min = 4, max =20, higher scores mean is worse outcome | 15 minutes after extubation |