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| ID | Type | Description | Link |
|---|---|---|---|
| 2011-A00051-40 | Other Identifier | ANSM |
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The primary objective is to show that positive pressure extubation improves oxygenation immediately after extubation compared to extubation via "aspiration" by evaluating and comparing the onset time of desaturation during spontaneous ventilation during awakening following general anesthesia.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Positive pressure extubation | Active Comparator | Positive pressure extubation will be used for patients waking up from general anesthesia in this group |
|
| Aspiration/suction extubation | Active Comparator | Aspiration/suction extubation will be used for patients waking up from general anesthesia in this group |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Positive pressure extubation | Procedure | Positive pressure extubation will be used for patients waking up from general anesthesia |
|
| Measure | Description | Time Frame |
|---|---|---|
| Spontaneous ventilation (air) time without desaturation after extubation (min) | desaturation is defined as an SpO2< 92% | 10 minutes |
| Measure | Description | Time Frame |
|---|---|---|
| presence/absence of a desaturation after extubation | desaturation is defined as an SpO2<92% | 10 minutes |
| minimum Sp02 level after extubation (%) | 10 minutes |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Joël L'Hermite, MD | Centre Hospitalier Universitaire de Nīmes | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Centre Hospitalier Universitaire de Nîmes | Nîmes | Gard | 30029 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 28882741 | Result | L'Hermite J, Wira O, Castelli C, de La Coussaye JE, Ripart J, Cuvillon P. Tracheal extubation with suction vs. positive pressure during emergence from general anaesthesia in adults: A randomised controlled trial. Anaesth Crit Care Pain Med. 2018 Apr;37(2):147-153. doi: 10.1016/j.accpm.2017.07.005. Epub 2017 Sep 4. |
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| Aspiration/suction extubation | Procedure | Aspiration/suction extubation will be used for patients waking up from general anesthesia |
|
| minimum Sp02 level after extubation (%) | 60 minutes |
| presence/absence of complications | coughing, airway obstruction, laryngospasm, desaturation, apnea, vomiting in the first hour | 60 minutes |
| presence / absence of therapeutic maneuvers | includes oxygen therapy (or bezel ventimasque), Guedel airway, mask assistance, re-intubation during the first hour | 60 minutes |
| presence/absence of any complication | 60 minutes |