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The purpose of this study is to determine the effects of consuming a small breakfast of juice and toast with added phytate or with taking a folic acid supplement on the absorption of a small amount of zinc that is either bound to amino acids or to chloride or picolinate. The results of this study will provide new information on how components of diet (e.g., phytate, and folic acid) affect the absorption of different forms of dietary zinc (e.g., zinc bound to amino acids, zinc chloride, and zinc picolinate).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Zinc absorption study | Other | Zinc absorption is determined from each of 3 test meals in all subjects. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Regular toast and juice | Other | Participants consume a single test meal composed of regular whole wheat toast and apple juice, and zinc absorption is measured. |
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| Measure | Description | Time Frame |
|---|---|---|
| Fractional zinc absorption | Oral zinc tracer to tracee ratio in plasma, as a fraction of intravenous zinc tracer to tracee ratio | 48 hours |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Janet C King, Ph.D. | University of California, Berkeley | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of California | Berkeley | California | 94720 | United States |
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| High phytate toast and juice | Other | Participants consume a single test meal composed of high phytate whole wheat toast and apple juice, and zinc absorption is measured. |
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| Regular toast and juice, with folic acid | Other | Participants consume a single test meal composed of regular whole wheat toast and apple juice, with 400 mcg folic acid; and zinc absorption is measured. |
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