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| Name | Class |
|---|---|
| University of Zurich | OTHER |
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The goal of this trial is to evaluate zinc citrate, a zinc compound with promising sensory properties and a high zinc content, as an alternative zinc compound to be used for supplementation or food fortification. The bioavailability of zinc citrate given as a supplement to young Swiss adults will be assessed and compared to the bioavailability of the commonly used zinc compounds zinc gluconate and zinc oxide.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| zinc citrate | Experimental |
| |
| zinc gluconate | Active Comparator |
| |
| zinc oxide | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| zinc citrate | Dietary Supplement | 10 mg of zinc as either zinc citrate |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Fractional absorption of zinc | Fractional absorption of zinc is estimated by using the double isotope tracer ratio technique by administering 67Zn as oral and 70Zn as intravenous stable isotopes.The urinary enrichment with both isotopes is measured in a spot urine sample by inductively coupled plasma mass spectrometry. | 61 days |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| ETH Zurich | Zurich | 8092 | Switzerland |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 24259556 | Derived | Wegmuller R, Tay F, Zeder C, Brnic M, Hurrell RF. Zinc absorption by young adults from supplemental zinc citrate is comparable with that from zinc gluconate and higher than from zinc oxide. J Nutr. 2014 Feb;144(2):132-6. doi: 10.3945/jn.113.181487. Epub 2013 Nov 20. |
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| ID | Term |
|---|---|
| C030691 | gluconic acid |
| D015034 | Zinc Oxide |
| ID | Term |
|---|---|
| D010087 | Oxides |
| D017601 | Oxygen Compounds |
| D007287 | Inorganic Chemicals |
| D017967 | Zinc Compounds |
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| Zinc Gluconate |
| Dietary Supplement |
10 mg of zinc as either zinc gluconate |
|
| Zinc oxide | Dietary Supplement | 10 mg of zinc as either zinc oxide |
|