Comparative Single-dose Bioavailability Clinical Study of Different Coenzyme Q10 Products

The Single-centre, Randomized, Comparative Single-dose Bioavailability Clinical Study of Different Coenzyme Q10 Products

The randomized, open-label, three period crossover single-dose bioavailability study with three coenzyme Q10 products

The randomized, open-label, three period crossover single-dose bioavailability study with three coenzyme Q10 products will include 25 subjects who will test three different coenzyme Q10 products. Serum concentration of coenzyme Q10 will be measured.

Inclusion Criteria:

• subject informed consent form
• aged between 40 and 55 years old
• body mass for women 65± 5 kg and for men 85± 5 kg
• non-smoking
• healthy, without cardio-vascular diseases, diabetes, neurodegenerative diseases
• absence of any prescribed medication during the study
• willing to avoid a consumption of any food supplements at least 2 weeks before and during the study
• willing to study all study procedures

Exclusion Criteria:

• cardio-vascular diseases,
• diabetes,
• neurodegenerative diseases,
• gastrointestinal disorders
• hypotension
• pregnancy
• breast-feeding
• intake of any prescribed medication within two week of the beginning of the study
• intake of any food supplements within two week of the beginning of the study
• drug or alcohol abuse