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| Name | Class |
|---|---|
| Medical Research Council, South Africa | OTHER |
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The study evaluates the impact of a personal and domestic hygiene intervention on exposure to lead in a community close to a mine dump. A before and after intervention study will be conducted in a selected area to determine lead exposure levels and the reduction or not after application of the intervention.
A before and after intervention study will be conducted with a control and intervention group, where data will be collected at the household (through questionnaire based interviews, floor and/or windowsill samples and soil samples collection) and individual level (through hand dust wipe sample collection). In phase one, both the control and intervention group will be interviewed, household floor and/or windowsill dust wipes will be taken, yard soil sample collected and hand dust wipe samples will be taken from children in participating households. After baseline data collection, participants will be allocated into either intervention or control group. The intervention group will participate in the domestic hygiene demonstration and educational discussion.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Intervention group | Experimental | The group that will receive the intervention to apply |
|
| Control group | No Intervention | The group that will not receive the intervention |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Domestic Hygiene and household hygiene Intervention | Behavioral | A demonstration on the domestic hygiene intervention will be conducted where participants will be guided on optimal cleaning of windowsills, floors and other surfaces with water and detergent, and advised on appropriate method of cleaning. Participants will be provided with a package of cleaning materials (mop, bucket, detergent, hand wash liquid soap and cloth for wet dusting) which will be used during the demonstration, and retained by participants to facilitate sustainability of the intervention during and after the study. Participants will be further engaged in an educational discussion, with the aid of a specially designed educational pamphlet containing information about health effects potentially associated with dust lead exposure from mine dumps and the personal hygiene and domestic hygiene steps that may be followed to reduce dust lead exposure. |
| Measure | Description | Time Frame |
|---|---|---|
| Lead exposure level | To detect a mean difference in change from baseline to follow-up of -0.5 μg/dL between the control and experimental group, with common standard deviation of 2 μg/dL | Three months |
| Measure | Description | Time Frame |
|---|---|---|
| Reference Lead exposure level | A reference level of 5.0 μg/dL for public health intervention of exposure to lead | Three months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Makhutsisa C Mokoatle, Masters | University of Johannesburg | Principal Investigator |
| Vusumuzi Nkosi, PhD | Medical Research Council, South Africa | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Snake Park, Soweto | Johannesburg | Gauteng | 1863 | South Africa |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 35658916 | Derived | Mokoatle C, Mathee A, Street R, Nkosi V. A study protocol to evaluate the impact of a personal and domestic hygiene intervention on lead exposure in a community next to a mine dump. BMC Public Health. 2022 Jun 4;22(1):1123. doi: 10.1186/s12889-022-13439-8. |
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All collected IDP to be shared
Through out the duration of the study up to a period of five years
Only the research team will access IPD for capturing and analysis of covariance and descriptive statistics.
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Participants are divided into two groups and one group is assigned to one household hygiene and an educational intervention which they apply and the impact of the intervention on lead exposure is assessed and the other group has no intervention.
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|
| ID | Term |
|---|---|
| D007855 | Lead Poisoning |
| ID | Term |
|---|---|
| D000075322 | Heavy Metal Poisoning |
| D011041 | Poisoning |
| D064419 | Chemically-Induced Disorders |
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