Cell-Based Noninvasive Prenatal Testing

Improving Methods for Cell-Based Noninvasive Prenatal Testing (NIPT)

The purpose of the overall study is to develop improved methods for recovery and analysis of fetal cells from the mother's blood in order to develop clinically useful forms of cell-based, diagnostic, noninvasive prenatal testing (NIPT). Luna genetics will obtain and analyze research blood samples from healthy pregnant women. A phlebotomist will be sent to any location in the United States to collect the blood samples. Sample identifiers will be removed as the first step so that laboratory personnel will not see or have access to identifiers.

Inclusion Criteria for healthy pregnant subjects:

• Pregnant
• 18 years or older
• 65 or younger

Exclusion Criteria for healthy pregnant subjects:

• Acute illness
• Unavailability of maternal blood sample of at least 30 ml
• Language barrier (non-English speaking )
• Maternal age of less than 18 years, or over 65
• Higher order multiple pregnancy (triplet or greater)