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| Name | Class |
|---|---|
| Belarusian State Medical University | OTHER |
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Treatment of age-related macular degeneration using retinal stem and progenitor cells
The aim of the project is to develop a biomedical cell product based on retinal pigment epithelium cells for highly effective treatment age-related macular degeneration; to conduct the clinical trials of the biomedical cell product in the treatment of age-related macular degeneration.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients with age-related macular degeneration receiving standard treatment and retinal stem cells | Experimental | Patients with age-related macular degeneration receiving standard treatment and autologous retinal stem and progenitor cells |
|
| Patients with age-related macular degeneration receiving standard treatment | Active Comparator | Patients with age-related macular degeneration receiving standard treatment |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Cultured retinal stem and progenitor cells | Biological | Cultured retinal stem and progenitor cells injected subretinally |
|
| Measure | Description | Time Frame |
|---|---|---|
| Visual acuity | Determination of visual acuity after the therapy | 1 month |
| Visual acuity | Determination of visual acuity after the therapy | 1 year |
| Adverse effects associated with the therapy | Determination of adverse effects associated with the therapy | 1 month |
| Adverse effects associated with the therapy | Determination of adverse effects associated with the therapy | 1 year |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Ludmila Marchenko, Prof | Belarusian State Medical University | Study Director |
| Zinaida Kvacheva, Dr | the Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus | Minsk | 220072 | Belarus |
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| Standard treatment according to the clinical protocols | Other | Standard treatment of age-related macular degeneration according to the clinical protocols |
|
| ID | Term |
|---|---|
| D008268 | Macular Degeneration |
| ID | Term |
|---|---|
| D012162 | Retinal Degeneration |
| D012164 | Retinal Diseases |
| D005128 | Eye Diseases |
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