The Metabolic and Circadian Effects of Shift Work

The Metabolic and Circadian Effects of Shift Work - An Observational Study

In an exploratory observational pilot study, the investigators will focus on the effects of short-term circadian misalignment induced by shift work on multidimensional measurements including glucose excursion, metabolic health, circadian rhythms (measured in vitro and in vivo), sleep/wake cycles and ambient light, eating and activity patterns, well-being and attention.

Inclusion Criteria:

• Men and women
• Age 20-50 years
• Working ≥ 80% full-time equivalent over the previous month and during the study
• Working night shifts (i.e. shifts that comprise working hours between 23h and 06h) in rotation with day shifts (i.e. shifts that comprise working hours between 06h and 20h)
• Planned to work at least 3 consecutive night shifts during the study preceded by at least a day off or day shift
• Planned to work at least 3 consecutive day shifts during the study
• Confident use of a smartphone compatible with the study application (iOS, Android) and able to regularly take pictures of consumed food/drinks
• Able to give a fully informed consent and follow the study procedures

Exclusion Criteria:

• Planned or current pregnancy during the study
• Menopausal women
• Major illness or hospitalization over the previous month
• Carries a pacemaker, pump or other medical device that can be disabled by a magnet
• Major mental illness
• Trip to a different time zone (≥ 2-hour time difference) over the previous month or planned during the study
• Enrolled in an interventional clinical trial (potentially interfering with the main outcomes) over the previous month or planned during the study