SIRT1 Gene Polymorphism With Premature Myocardial Infarct... | NCT05160844

Studies
SIRT1 Gene Polymorphism With Premature Myocardial Infarction in Young Egyptian Patients

NCT05160844

Sponsor

Sohag University

Status

Completed

Last Update Posted

Jul 9, 2024Actual

Enrollment

280Actual

Phase

Not provided

Conditions

Premature Myocardial Infarction in Young Egyptian Patients

Interventions

Not provided

Countries

Egypt

Protocol Section

Identification Module Status Module Sponsor/Collaborators Module Oversight Module Description Module Conditions Module Design Module Arms/Interventions Module Outcomes Module Eligibility Module Contacts/Locations Module References Module IPD Sharing Statement Module

Results Section

Participant Flow Module Baseline Characteristics Module Outcome Measures Module Adverse Events Module More Info Module

Annotation Section

Annotation Module

Document Section

Large Document Module

Derived Section

Miscellaneous Info Module Condition Browse Module Intervention Browse Module

Protocol Section

Identification Module

NCT ID

Results Section

No data available

No data is available for this block.

Annotation Section

No data available

No data is available for this block.

Document Section

No data available

No data is available for this block.

Derived Section

Miscellaneous Info Module

Version Holder

Status Module

Record Verification Date

Jul 2024

Overall Recruitment Status or Expanded Access Status

Completed

Last Known Status

Not provided

Delayed Posting

Not provided

Why Stopped

Not provided

Expanded Access Info

Start Date

Sep 1, 2021Actual

Primary Completion Date

Sep 1, 2023Actual

Completion Date

Jan 1, 2024Actual

First Submitted Date

Dec 6, 2021

First Submission Date that Met QC Criteria

Dec 6, 2021

First Posted Date

Dec 16, 2021Actual

Results Waived

Not provided

Results First Submitted Date

Not provided

Results First Submitted that Met QC Criteria

Not provided

Results First Posted Date

Not provided

Certification/Extension (aka Delayed Results) First Submitted Date

Not provided

Certification/Extension First Submitted that Passed QC Review

Not provided

Certification/Extension First Posted Date

Not provided

Last Update Submitted Date

Jul 7, 2024

Last Update Posted Date

Jul 9, 2024Actual

Oversight Module

Has Data Monitoring Committee (DMC)

Is FDA Regulated Drug

Is FDA Regulated Device

Is Unapproved Device

Not provided

Pediatric Postmarket Surveillance of a Device Product

Not provided

Product Exported from US

Not provided

FDAAA801 Violation

Not provided

Description Module

Brief Summary

This is an observertional study aimed at Study the association of SIRT1(rs7069102 ) Gene polymorphism with premature myocardial infarction in young Egyptian patients

Detailed Description

Not provided

Design Module

Study Type

Observational

Number of References to an Expanded Access Study

Not provided

Expanded Access Types

Not provided

Patient Registry

Target Follow-Up Duration

Not provided

Phases

Not provided

Interventional Study Design

Allocation

Not provided

Intervention Model

Biospecimen

No data available

No data is available for this block.

Enrollment

280Actual

Arms/Interventions Module

Arm Groups

Label	Type	Description	Intervention Names
Diseased		young Egyptian patients with premature myocardial infarction
Control		healthy young Egyptians

Interventions

Not provided

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
Endothelial nitric oxide synthase level	detect the serum level of Endothelial nitric oxide synthase by ELIZA in nanogram per millilitre (ng/ml)	6 months
SIRT1 Genotyping	whether homgenetic or heterogenetic	6 months

Secondary Outcomes

Not provided

Other Outcomes

Not provided

Eligibility Module

Eligibility Criteria

Inclusion Criteria:

All patient with recent MI admitted to Sohag University Hospital , CCU under 40 years

Exclusion Criteria:

patients above 40 year old.
Patients with malignancies, major trauma or surgery in the previous six months, and acute or chronic infectious disease

Accepts Healthy Volunteers

Yes

Sex

All

Sex/Gender Based

Not provided

Sex/Gender Description

Not provided

Minimum Age

18 Years

Maximum Age

40 Years

Standard Ages

Adult

Study Population

young egyptian patients under 40 years of age presented with recent MI admitted to CCU at sohag university hospital.

Sampling Method

Probability Sample

Contacts/Locations Module

Central Contacts

Not provided

Overall Officials

Name	Affiliation	Role
Amera Morad Foad hamdy, lecturer	Sohag faculty of medicine	Principal Investigator

Locations

Facility	Status	City	State	ZIP	Country	Contacts
Sohag uniersity hosoital		Sohag			Egypt