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The primary aim of this study was to compare the effects of two different low-dose bupivacaine used in spinal anesthesia on intraoperative hemodynamics in cesarean section operations.Investigators think that low-dose bupivacaine and fentanyl mixture applied in cesarean section cause fewer hemodynamic changes,provide adequate anesthesia and analgesia quality,cause fewer side effects,and postoperatively,patients may return to their daily activities more quickly.This study was conducted on 80 pregnant women undergo an elective cesarean section.Patients were randomly allocated in GrupA and GroupB. Combined spinal-epidural anesthesia was performed in the sitting position using the needle-inside-needle technique.After cerebrospinal fluid flow was observed, GroupA patients were given a solution containing 5 mg isobaric bupivacaine+15 µg fentanyl (1.3 ml),and Group B was administered a solution containing 7 mg isobaric bupivacaine+15 µg fentanyl (1.7ml).Hypotension,bradycardia,duration of analgesia,postoperative nausea and vomiting were recorded.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group İzobarik bupivakain (5 mg) + fentanil | Active Comparator | Patients were given a solution containing 5 mg isobaric bupivacaine + 15 µg fentanyl (1.3 ml) |
|
| Group İzobarik bupivakain (7 mg) + fentanil | Active Comparator | Patients were givena solution containing 7 mg isobaric bupivacaine + 15 µg fentanyl (1.7 ml) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Bupivacaine | Drug | Two Different Low-Doses Of Isobaric Bupivacaine ( Group İzobarik bupivakain (5 mg) + fentanil and Group İzobarik bupivakain (7 mg)+ fentanyl ) were administered to the subarachnoid space |
| Measure | Description | Time Frame |
|---|---|---|
| The primary aim of study was to compare the effects of two different low-dose bupivacaine used in spinal anesthesia on intraoperative systolic and diastolic blood pressure (mmHg) in cesarean section operations. | Intraoperatif hemodynamics | during cesarean procedure |
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Inclusion Criteria
Exclusion Criteria:
pregnant women
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| Name | Affiliation | Role |
|---|---|---|
| Mehmet Aksoy, MD | Ataturk University, Department of Anesthesiology and Reanimation | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Aysenur Dostbil | Yakutiye | Erzurum | 25000 | Turkey (Türkiye) |
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| ID | Term |
|---|---|
| D002045 | Bupivacaine |
| ID | Term |
|---|---|
| D000813 | Anilides |
| D000577 | Amides |
| D009930 | Organic Chemicals |
| D000814 | Aniline Compounds |
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| D000588 |
| Amines |