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| ID | Type | Description | Link |
|---|---|---|---|
| TDK-2020-22186 | Other Grant/Funding Number | Ege University Scientific Research Project Coordination Unit |
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Bone morphogenetic protein (BMP) 9 from the BMP family has an important role in the remodeling of bone and cartilage. Due to these features, BMP9 can play an important role in especially anaerobic exercise training adaptations. However, the role of anaerobic exercise in these effects is still unclear. The aim of this study is to investigate the role of BMP9 on the effects of acute and chronic anaerobic exercise on bone metabolism markers. Postprandial venous blood samples were taken pre- and post- acute YOYO intermittent recovery test (level 1) in 40 trained male athletes aged 18-35 who did anaerobic sports (such as basketball, volleyball and handball) and 41 sedentary volunteers aged 18-35. Serum BMP9, as markers of bone formation and resorption; alkaline phosphatase (ALP), C-terminal telopeptide of type 1 collagen (CTX1), cartilage oligomeric matrix protein (COMP) and calcium levels were determined. The data to be obtained as a result of our study can give information about the relationship between the skeletal and bone health of the athletes and anaerobic exercise.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Athletic group | Healthy male athletes who have been doing regular anaerobic sports (such as basketball, volleyball and handball) for at least 3 months |
| |
| Control group | Healthy sedentary (not doing regular sports for at least 3 months) men with age and physical characteristics similar to the athlete group |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Physiological test | Other | This test was conducted to determine the endurance levels of the participants. |
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| Measure | Description | Time Frame |
|---|---|---|
| Change from serum BMP9 levels at pre- and post- YOYO intermittent test | Postprandial venous blood samples were obtained before and after acute YOYO IR test (level 1). The YOYO test lasted 10-20 minutes depending on the ability level of the participants. A blood sample was taken 15 minutes before and 15 minutes after the YOYO test. From these blood samples, serum Bone morphogenetic protein 9 (BMP9) was determined. | between 40-50 minutes |
| Change from serum CTX1 levels at pre- and post- YOYO intermittent test | Postprandial venous blood samples were obtained before and after acute YOYO IR test (level 1). The YOYO test lasted 10-20 minutes depending on the ability level of the participants. A blood sample was taken 15 minutes before and 15 minutes after the YOYO test. From these blood samples, serum C-terminal telopeptide of Type 1 collagen (CTX1) was determined. | between 40-50 minutes |
| Change from serum COMP levels at pre- and post- YOYO intermittent test | Postprandial venous blood samples were obtained before and after acute YOYO IR test (level 1). The YOYO test lasted 10-20 minutes depending on the ability level of the participants. A blood sample was taken 15 minutes before and 15 minutes after the YOYO test. From these blood samples, serum cartilage oligomeric matrix protein (COMP) was determined. | between 40-50 minutes |
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Inclusion Criteria:
Exclusion Criteria:
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Athletic group: trained male athletes who did anaerobic sports (such as basketball, volleyball and handball) Control group: sedentary males
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| Name | Affiliation | Role |
|---|---|---|
| Faruk Turgay | Ege University Faculty of Sport Sciences | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ege University Faculty of Sport Sciences | Izmir | 35040 | Turkey (Türkiye) |
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| ID | Term |
|---|---|
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D001519 | Behavior |
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| ID | Term |
|---|---|
| D005080 | Exercise Test |
| ID | Term |
|---|---|
| D006334 | Heart Function Tests |
| D003935 | Diagnostic Techniques, Cardiovascular |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
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| Physical test | Other | Height, weight, and BMI were determined |
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| Biochemical tests | Other | BMP9, CTX1, COMP, oxLDL protein levels, ALP, GGT, TAS, TOS, OSI, NO, calcium, T-C, LDL-C, Triglyceride, HDL-C, glucose, CRP, AST, ALT, erythrocyte, mean erythrocyte volume (MCV), hematocrit, leukocyte, thrombocyte levels were determined from blood samples. |
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| D012129 | Respiratory Function Tests |
| D003948 | Diagnostic Techniques, Respiratory System |
| D016552 | Ergometry |
| D008919 | Investigative Techniques |