Long-term Cohort Study of Mesorectal Excision for Rectal Cancer

Long-term Cohort Study of Mesorectal Excision for Rectal Cancer

The aim of this cohort study is to record, evaluate and compare the surgical, oncological as well as the functional outcome and Quality of life after mesorectal excision for rectal cancer

Outcomes of mesorectal excision patients will be analysed. Medical records will be reviewed and perioperative outcomes retrieved, incl. long-term oncological and functional/quality of life data. A retrospective cohort over 10 years (2007-2016) will serve as a control to a prospective cohort over 10 further years (2017-2026) as to investigate trends in perioperative and oncological outcomes (min. follow-up of 5 years + adequate cohort size). Prospective data on bowel function, urogenital function and quality of life will measured at time of diagnosis and further. Variations in neoadjuvant/adjuvant treatment and surgical approaches will be assessed for their effect on the outcomes of interest.

Inclusion Criteria:

• Men and Women >18 years
• Patients with rectal cancer
• Underwent mesorectal excision
• Agreed to fill in a validated questionnaires before surgery and after stoma reversal
• Informed consent

Exclusion Criteria:

• Age < 18
• No informed consent (no general consent, no consent to use personal data for research purpose)