Protective effect of Beraprost Sodium Tablets on coronary microcirculation function and ventricular remodeling after reperfusion therapy for acute ST segment elevation myocardial infarction

Inclusion Criteria:

• It meets the diagnostic criteria of acute ST segment elevation myocardial infarction: ischemic chest pain lasts for more than 30 minutes and can not be relieved by taking nitroglycerin; ST segment elevation of ECG with two or more adjacent leads, limb lead ≥ 1mm, chest lead ≥ 2mm; Or new left bundle branch block; The serum markers of myocardial necrosis increased at least twice the normal value
• Acute myocardial infarction was confirmed by coronary angiography
• The clinical and angiographic data were complete
• Direct PCI was performed within 12 hours after onset

Exclusion Criteria:

• Those who do not cooperate in the inspection, have poor compliance and cannot guarantee the completion of the test
• Conscious disorder, obvious intellectual disorder and mental disorder
• With metal foreign bodies, such as metal prosthesis, intraocular metal foreign bodies, intracranial aneurysm clamp, etc
• People with claustrophobia
• Had a history of myocardial infarction, PCI and coronary artery bypass grafting
• Factors affecting ST segment changes of ECG: complete left bundle branch block, preexcitation syndrome, pacemaker ECG, etc