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| ID | Type | Description | Link |
|---|---|---|---|
| 201502022 | Other Grant/Funding Number | Research Special Fund for Public Welfare Industry of Health |
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| Name | Class |
|---|---|
| Jiangsu Cancer Institute & Hospital | OTHER |
| Subei People's Hospital of Jiangsu Province | OTHER |
| Peking Union Medical College | OTHER |
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The present study aims to investigate the prognostic value of preoperative fat-free mass index for postoperative outcomes in patients undergoing esophagogastric cancer surgery, and to explore the role of the FFMI in the Global Leadership Initiative on Malnutrition (GLIM) criteria.
The GLIM criteria of malnutrition as a consensus lack of optimal combination in clinical validation. After the publication of the GLIM consensus, few studies have examined the effect of reduced FFMI on the clinical prognosis of patients with esophagogastric cancer, and whether the FFMI can be used as an effective diagnostic criterion of malnutrition in esophagogastric cancer needs to be further studied.
Therefore, the present study aims were to investigate the prognostic value of preoperative fat-free mass index for postoperative outcomes in patients undergoing esophagogastric cancer surgery, and to explore the role of the FFMI in the GLIM consensus for malnutrition.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| The normal FFMI group | The FFMI was calculated as follows: FFMI = fat-free mass (kg)/height squared (m2). FFMI cut-off values (derived from BIA measurements, \ |
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| The low FFMI group | The FFMI was calculated as follows: FFMI = fat-free mass (kg)/height squared (m2). FFMI cut-off values (derived from BIA measurements, \ |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| no intervention | Other |
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| Measure | Description | Time Frame |
|---|---|---|
| postoperative complications | postoperative complications (infectious complications and noninfectious complications) | Within 60 days after surgery |
| Measure | Description | Time Frame |
|---|---|---|
| length of stay (LOS) | length of stay (LOS) | Within 60 days after surgery |
| wound healing time | wound healing time | Within 60 days after surgery |
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Inclusion Criteria:
Elective surgery for esophagogastric cancer (there was a clear pathological diagnosis before surgery); NRS2002≥3; Preoperative BIA examination was performed.
Exclusion Criteria:
Discharged from a hospital within 24 hours; No BIA examination and not suitable for BIA examination (such as ascites, edema, amputation and pace-maker); Hepatic insufficiency (alanine transaminase/aspartate transaminase ratio 200% above normal range or bilirubin>3mg/dL) ; Renal insufficiency (serum creatinine>1.5mg/dL); Emergency operation; Pregnancy; Missing the postoperative information follow-up data.
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Elective surgery for esophagogastric cancer (there was a clear pathological diagnosis before surgery)
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| ID | Term |
|---|---|
| D013274 | Stomach Neoplasms |
| D004938 | Esophageal Neoplasms |
| D044342 | Malnutrition |
| D009133 | Muscular Atrophy |
| D009369 | Neoplasms |
| D011183 | Postoperative Complications |
| ID | Term |
|---|---|
| D005770 | Gastrointestinal Neoplasms |
| D004067 | Digestive System Neoplasms |
| D009371 | Neoplasms by Site |
| D004066 | Digestive System Diseases |
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| postoperative antibiotic time | postoperative antibiotic time | Within 60 days after surgery |
| nutritional status | nutritional status ( such as: weight,albumin,prealbumin) | up to 4 weeks |
| hospitalization cost | hospitalization cost(including: surgery and medicine costs) | Within 60 days after surgery |
| D005767 | Gastrointestinal Diseases |
| D013272 | Stomach Diseases |
| D006258 | Head and Neck Neoplasms |
| D004935 | Esophageal Diseases |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
| D020879 | Neuromuscular Manifestations |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D001284 | Atrophy |
| D020763 | Pathological Conditions, Anatomical |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D012816 | Signs and Symptoms |
| D010335 | Pathologic Processes |