This study aims to determine whether changes in retinal vasculature seen on SS-OCTA can be correlated to degree of cardiovascular disease as measured by carotid duplex ultrasonography.

The study's primary objective is to determine whether measures taken from SS-OCTA, color fundus photography, and retinal exams can correlate with and predict the presence/degree of carotid occlusive disease as determined by carotid duplex ultrasonography by examining the following parameters: retinal vessel caliber, retinal vessel density, retinal vessel perfusion, retinal vessel tortuosity, presence of Hollenhorst or other plaques, and/or areas of ischemia.

Inclusion Criteria:

• Subjects between 18 and 95 years of age
• Able to participate in a clinical eye examination setting
• Able to consent
• Subjects receiving standard of care carotid duplex ultrasounds

Exclusion Criteria:

• Inability to get high quality imaging for any reason (ex. Dense cataract, media opacity)
• Lack of capacity to provide informed consent
• Subjects younger than 18 years of age or older than 95 years of age
• History of stroke or acute loss of vision
• Unable to participate in a clinical eye examination setting

These subjects were identified in the Northwestern Medicine Division of Vascular Surgery during their standard of care visit.