Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
This study aims to
At the end of 2019, the COVID-19 pandemic broke out in Wuhan, China, and within few months -in March 2020- it was declared a pandemic by the WHO.
As of September 15th ,2021, there have been 226,844,344 confirmed cases of COVID-19, including 4,666,334 deaths, reported to WHO (1).
Due to the prevalence of COVID-19 and the financial burden it puts on the healthcare system, the use of a simple, affordable and reliable imaging modality was necessary.
The main idea in this research will be evaluating the value of Lung Ultrasonography Score in predicting the prognosis of patients with COVID-19 pneumonia and investigate the presence of a relation between the Lung Ultrasonography Score and patients' prognosis and mortality (2).
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Lung Ultrasonography | Device | The ultrasonography will be done using the curved probe of the SONOACE R3 SAMSUNG ultrasonography machine, SN: S0GYM3HCC00016M, manufacture date: 12-2012. Assessment of lung condition using the Lung Ultrasonography Score (total score calculated from the 12 standard examined areas, from 0 to 3 in each area, with a minimum of 0 up to 36) |
| Measure | Description | Time Frame |
|---|---|---|
| Correlation between Lung Ultrasonography Score and condition severity (inflammatory markers) | creation of a statistical relation between the Lung Ultrasonography Score and the severity of the condition, which is assessed by clinical examination and inflammatory markers. | through study completion, an average of 2 years. |
| Mortality | creation of a statistical relation between the Lung Ultrasonography Score and mortality. | Through study completion, an average of 2 years. |
| Measure | Description | Time Frame |
|---|---|---|
| Ventilatory support. | creation of a statistical relation between the Lung Ultrasonography Score and the ventilatory support needed by the patients. | Through study completion, an average of 2 years. |
| Duration of hospital stay |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Sample size calculation will be carried out using G*Power 3 software , A minimum calculated sample of 60 COVID-19 cases will be needed to detect an effect size of 0.2 (22%-70%) vs (40%-93%) in the diagnostic yield (sensitivity and specificity) of lung US in severity of COVID-19 diagnosis, with an error probability of 0.05 and 80% power on a one-tailed test
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Karim O Sleem, BMBS | Contact | 0201008955986 | karimosama81@gmail.com | |
| Mohammed S Abdel-Qader, Ph.D M.D | Contact | 0201060507372 | mohamed.saad85@yahoo.com |
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Assiut University Hospital | Recruiting | Asyut | 71111 | Egypt |
Not provided
| Label | URL |
|---|---|
| WHO dashboard for updated COVID-19 statistics | View source |
| 3- Brenner, D.S., Liu, G.Y., Omron, R. et al. Diagnostic accuracy of lung ultrasound for SARS-CoV-2: a retrospective cohort study. Ultrasound J 13, 12 (2021) | View source |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Assessment of relation between Lung Ultrasonography Score and the duration of hospital stay.
| Through study completion, an average of 2 years. |
| ICU Admission | Assessment of relation between Lung Ultrasonography Score and the ICU admission. | Through study completion, an average of 2 years. |
| 4- Faul, F., Erdfelder, E., Lang, A.-G. \& Buchner, A. (2007). G\*Power 3: A flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behavior Research Methods, 39, 175-191 |
| View source |
| 5- de Alencar, J.C.G., Marchini, J.F.M., Marino, L.O. et al. Lung ultrasound score predicts outcomes in COVID-19 patients admitted to the emergency department. Ann. Intensive Care 11, 6 (2021). https://doi.org/10.1186/s13613-020-00799-w | View source |