High Versus Low Blood-Pressure Target in the Post Operative Care of Liver Transplantation A Randomized, Controled, Open and Unicentric Trial.

High Versus Low Blood-Pressure Target in the Post Operative Care of Liver Transplantation

LIVER PAM

A randomized, controled, open and unicentric trial comparing high (MAP 85-90 mmHg) and low (65-70 mmHg) target of mean arterial pressure in the first 24 hours after liver transplantation.

Inclusion Criteria:

• Older than 18 y
• Admitted in the ICU for a post operative care after liver transplant

Exclusion Criteria:

• Consent refusal
• Liver transplant due to acute liver failure
• Renal transplant ( Previous or concomitant)
• Refusal from the healthcare provider responsible for the patient
• Renal substitution therapy in the prior 15 days
• Pregnancy
• Re-Transplant (Liver transplant in the previous 6 month)
• Hepatorenal syndrome current treatment (Use of terlipressin + Albumin)
• Refractory and persistent shock during or after transplant