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The study of the diaphragm is an important point in the assessment of COPD patients.
Ultrasonographic evaluation of the diaphragm is considered a simple, non-invasive, available bedside technique. Ultrasonography can be used for evaluation of the site, structure, and motion of the diaphragm, assessment of excursion, and thickness.
The aim of the study is ultrasonographic assessment of the diaphragm in COPD patients and its relation to disease severity
The study was conducted on eighty patients, forty COPD patients who were diagnosed and classified into four groups according as following: The first group: included 10 patients with a mild stage. The second group: included 10 patients with a moderate stage. The third group: included 10 patients with a severe stage. The fourth group: included 10 patients with a very severe stage. The study also included forty healthy individuals of the same age and sex as COPD patients. All participants gave their informed consent for inclusion before sharing in the study. Every person was submitted to: Full medical history, Clinical examination,Chest x-ray, spirometry and ultrasonographic assessment of diaphragm function (thickness and excursion)
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 40 COPD patients | all participants were subjected to : history - clinical examination - spirometry - ultrasound evaluation of diaphragmatic function |
| |
| 40 healthy individuals | all participants were subjected to : history - clinical examination - spirometry - ultrasound evaluation of diaphragmatic function |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| ultrasonography | Device | ultrasound assessment of diaphragm function |
|
| Measure | Description | Time Frame |
|---|---|---|
| measure diaphragmatic thickness by ultrasound | measure diaphragmatic thickness at total lung capacity and residual volume in millimetres to calculate diaphragm thickness fraction | 1 year study |
| measure diaphragm excursion by ultrasound | measure diaphragm excursion in centimetres at zone of apposition | 1 year study |
| Measure | Description | Time Frame |
|---|---|---|
| spirometry assessment | value of forced expiratory volume in first second is assessed as a percentage of normal by spirometry to assess disease severity | 1 year study |
| questionnaires | ( modified medical research council and chronic obstructive pulmonary disease assessment test) to detect severity of the disease |
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Inclusion Criteria:
• Stable COPD patients aged more than 40 years who were diagnosed and classified into four groups of severity according to GOLD 2020.
Exclusion Criteria:
• Patient with a known neuromuscular disorder.
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40 COPD patients and 40 age matched healthy control
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| Name | Affiliation | Role |
|---|---|---|
| Enas S Farhat, MD | Fayoum University Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Fayoum University Hospital | Al Fayyum | Egypt |
after the submission is finished, the individual participant data will be shared to other researchers
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| ID | Term |
|---|---|
| D029424 | Pulmonary Disease, Chronic Obstructive |
| ID | Term |
|---|---|
| D008173 | Lung Diseases, Obstructive |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D002908 | Chronic Disease |
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| ID | Term |
|---|---|
| D014463 | Ultrasonography |
| ID | Term |
|---|---|
| D003952 | Diagnostic Imaging |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
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| 1 year study |
| D020969 |
| Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |