Multicenter observational study of diagnostic test validation (Research Involving the Human Person, type 3) In addition to the diagnosis by the reference method (nasopharyngeal swab), the patient will be asked to provide a saliva sample via a salivary spit. The clinical circumstances of the diagnosis, the age of the patient, the associated terrain (diabetes, immunodepression, pregnancy) will be noted. The nasopharyngeal and saliva samples will be analyzed in Cayenne and the remaining samples will be frozen and stored at the CRB before being sent to the University Hospital of Caen for analysis and concordance verification.

The expected benefits are:

Possibility of repeating tests in the same person more easily due to the absence of pain and thus reduce the barriers to diagnosis and screening.

Possibility of self-sampling, which could simply be sent to the laboratory, which would relieve the diagnostic sites that mobilize staff and require a fairly heavy organization. Avoid long waiting lines that can be an obstacle and lead to a renunciation of the diagnosis.

Inclusion Criteria:

• Patient with an indication to perform a COVID diagnostic test (symptomatology, contact case, systematic screening etc...)
• Men and women at least 3 years old

Exclusion Criteria:

• Refusal of the patient or his legal representative,
• Taking treatments that reduce salivary volume (anticholinergic activity)
• Impossibility to perform the nasopharyngeal test
• Patient under guardianship or curatorship, persons placed under protective measures