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Safety and Efficacy of Pilocarpine, Brimonidine, Oxymetazoline, Hyaluronic acid, Bromfenac (PBOHB) ophthalmic compound to improve uncorrected near vision in healthy presbyopic patients one hour after instillation.
To determine the safety and efficacy of a novel pharmacological compound of Pilocarpine, Brimonidine, Oxymetazoline, Hyaluronic acid, Bromfenac (PBOHB) to improve uncorrected near vision in healthy presbyopic patients one hour after binocular instillation.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| PBOHB | Experimental | Pilocarpine, Brimonidine, Oxymetazoline, Hyaluronic Acid, Bromfenac to evaluate safety and efficacy to improve uncorrected near vision in healthy presbyopic patients |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Pilocarpine, brimonidine, oxymetazoline, hyaluronic acid, bromfenac (PBOHB) compound | Drug | To determine the safety and efficacy of a PBOHB compound in near vision of presbyopic patients. |
| Measure | Description | Time Frame |
|---|---|---|
| Jaeger near uncorrected visual acuity improvement | Measure uncorrected near vision change after binocular instillation of PBOHB compound | 1 hour |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Cesar Alejandro S Galeana, MD | Contact | 5541851511 | optallvision@gmail.com | |
| Rosario Perez | Contact | 559199042 | optallvision@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Cesar Alejandro S Galeana, MD | Optall Vision | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Optall Vision | Recruiting | Mexico City | 01090 | Mexico |
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| ID | Term |
|---|---|
| D011305 | Presbyopia |
| ID | Term |
|---|---|
| D012030 | Refractive Errors |
| D005128 | Eye Diseases |
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| ID | Term |
|---|---|
| D010862 | Pilocarpine |
| D000068438 | Brimonidine Tartrate |
| D010109 | Oxymetazoline |
| D006820 | Hyaluronic Acid |
| C053083 | bromfenac |
| ID | Term |
|---|---|
| D000470 | Alkaloids |
| D006571 | Heterocyclic Compounds |
| D011810 | Quinoxalines |
| D006574 | Heterocyclic Compounds, 2-Ring |
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To determine safety and efficacy of a Pilocarpine, Brimonidine, Oxymetazoline, Hyaluronic Acid, Bromfenac compound to improve near uncorrected vision in healthy presbyopic patients
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|
| D000072471 |
| Heterocyclic Compounds, Fused-Ring |
| D007093 | Imidazoles |
| D001393 | Azoles |
| D006573 | Heterocyclic Compounds, 1-Ring |
| D006025 | Glycosaminoglycans |
| D011134 | Polysaccharides |
| D002241 | Carbohydrates |