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The need to restore water losses resulting from physical activity has become established and diffused into international consensus for healthy individuals or high-performance athletes. However, the influence of fluid replacement when administered during and after exercise on cardiac autonomic modulation with autonomic alterations known as the coronary arteries remain poorly understood. The aim of the study was to evaluate and compare whether different hydration strategies are able to promote acceleration of the recovery of autonomic modulation in individuals with coronary artery disease undergoing aerobic exercise. This study is a cross-over clinical trial, which will be developed based on an experimental procedure performed in four stages. A total of 31 individuals will be recruited in this study and will perform four standardized cardiovascular rehabilitation (CR) sessions. The participants will perform CR with mineral water intake in phase three and four. In phase three, the consumption will be done a quantity of water predetermined by the evaluator, based on the loss of body mass measured in the second session. In phase four, hydration will be carried out in an uncontrolled manner, according to the desire to drink water during the protocol.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control group | Active Comparator | Only treadmill aerobic exercise with 60 min recovery in supine position. |
|
| Controlled hydration group | Experimental | Treadmill aerobic exercise with 60 min recovery in supine position, with mineral water predetermined intake. |
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| Ad Libitum hydration group | Experimental | Treadmill aerobic exercise with 60 min recovery in supine position, with mineral water intake in an uncontrolled manner. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Treadmill aerobic exercise without water intake | Other | The volunteers will be submitted to a cardiovascular rehabilitation session with 40 minutes of treadmill aerobic exercise followed by 60 minutes of recovery at the supine position. |
| Measure | Description | Time Frame |
|---|---|---|
| Heart rate variability | Linear indices of heart rate variability in the time domain (SDNN, rMSSD). | up to six months |
| Heart rate variability | Linear indices of heart rate variability in the frequency domain (HF, LF, LF/HF) | up to six months |
| Heart rate variability | Geometric indices of heart rate variability (TINN, RRTRI, SD1, SD2, SD1/SD2) | up to six months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Lorena Santos, BPT | Contact | 55019992359245 | lorenaltafin@gmail.com | |
| Luiz Carlos Vanderlei, PhD | Contact | 55018997029639 | lcmvanderlei@fct.unesp.br |
| Name | Affiliation | Role |
|---|---|---|
| Luiz Carlos Vanderlei, PhD | Universidade Estadual Paulista - UNESP - Campus de Presidente Prudente | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Luiz Carlos Masques Vanderlei | Recruiting | Presidente Prudente | São Paulo | 19060-900 | Brazil |
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| Treadmill aerobic exercise with water intake of a predetermined amount. | Other | The volunteers will be submitted to a cardiovascular rehabilitation session with 40 minutes of treadmill aerobic exercise and water intake followed by 60 minutes of recovery at the supine position. |
|
| Treadmill aerobic exercise with water intake according to the desire to drink | Other | The volunteers will be submitted to a cardiovascular rehabilitation session with 40 minutes of treadmill aerobic exercise and water intake followed by 60 minutes of recovery at the supine position. |
|
| ID | Term |
|---|---|
| D003327 | Coronary Disease |
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D017202 | Myocardial Ischemia |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D014652 | Vascular Diseases |
| D001519 | Behavior |
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| ID | Term |
|---|---|
| D004326 | Drinking |
| ID | Term |
|---|---|
| D004435 | Eating |
| D009747 | Nutritional Physiological Phenomena |
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
| D004068 | Digestive System Physiological Phenomena |
| D055688 | Digestive System and Oral Physiological Phenomena |
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