Low Carbohydrate Small Intestine Study

Studying the Impact of a Low Carbohydrate Diet on the Small Intestinal Microbiota

The investigators will recruit probands with a ileo- or colostoma that are otherwise in good general health and analyse the stomal fluids for their microbiota composition. Sampling will be performed over a time span of 28 days, after 14 days probands will modify their base-line diet to a low carbohydrate diet.

Additionally to stoma fluids which will be analyzed for their microbiota composition the investigators will also collect skin samples to analyze for microbiota composition and urine to analyze for metabolite composition.

Low carbohydrate diet will allow for consumption of 80g complex carbohydrates per day, simple sugars will have to be avoided completely

Inclusion Criteria:

• Ileostomy or colostomy
• Good general health
• Written informed consent

Exclusion Criteria:

• Major metabolic diseases that prevent adherence to low carbohydrate diet
• Participation in other clinical trial interfering with study protocol