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This is a pragmatic, multi-center, prospective, observational, non-interventional study and standing database of patients hospitalized for transient ischemic attack (TIA) or stroke in the 11 accredited adult neurology training institutions in the Philippines. Data will be collected from each patient while admitted in the hospital and until hospital discharge. Data collection for this study will span 3 years from study initiation, after which the utility of an extension or a re-implementation of the study will be assessed.
Primary objective is to prospectively collect data on demographics, medical history, in-hospital management, and outcomes among patients with first or recurrent TIA or ischemic or hemorrhagic stroke admitted in accredited adult neurology training institutions in the Philippines.
Secondary objectives are:
All eligible patients will be assigned a study identification (ID) number and included in the site log kept confidentially in each site. Corresponding anonymized data on demographics, medical history, stroke sub-type, in-hospital management and discharge outcomes will be collected from each patient and entered in the database using a secure online data collection tool.
Collective data will be extracted, summarized, and analyzed for the secondary objectives every year with oversight provided by the Philippine Neurological Association.
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| Measure | Description | Time Frame |
|---|---|---|
| In-hospital caseload | Number of TIA and stroke cases admitted in participating sites. | 3 years |
| Measure | Description | Time Frame |
|---|---|---|
| In-hospital diagnostic procedure (brain scan) | Rate of performance of brain scan. | From admission to discharge, may be up to 1 month |
| In-hospital diagnostic procedures (electrocardiogram) | Rate of performance of electrocardiogram. |
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Inclusion Criteria:
Exclusion Criteria:
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All patients admitted at the participating sites fulfilling all inclusion and none of the exclusion criteria are eligible to be included.
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| Name | Affiliation | Role |
|---|---|---|
| Robert N Gan, MD | Philippine Neurological Association | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Baguio General Hospital and Medical Center | Baguio City | Benguet | Philippines | |||
| Chong Hua Hospital |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 35613760 | Derived | Philippine Neurological Association One Database - Stroke, Disease Study Management Group. Multicentre collection of uniform data on patients hospitalised for transient ischaemic attack or stroke in the Philippines: the Philippine Neurological Association One Database-Stroke (PNA1DB-Stroke) protocol. BMJ Open. 2022 May 24;12(5):e055954. doi: 10.1136/bmjopen-2021-055954. |
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| From admission to discharge, may be up to 1 month |
| In-hospital diagnostic procedures (echocardiogram) | Rate of performance of echocardiogram. | From admission to discharge, may be up to 1 month |
| In-hospital diagnostic procedures (cerebral vascular studies) | Rate of performance of any cerebral vascular study. | From admission to discharge, may be up to 1 month |
| In-hospital therapeutic management (thrombolysis) | Rate of treatment with thrombolysis (intravenous and/or endovascular). | From admission to discharge, may be up to 1 month |
| In-hospital therapeutic management (anti-thrombotics) | Rate of treatment with any anti-thrombotic (anti-platelet and/or anti-coagulant). | From admission to discharge, may be up to 1 month |
| In-hospital therapeutic management (rehabilitation) | Rate of rehabilitation (physical therapy and/or occupational therapy and or speech therapy). | From admission to discharge, may be up to 1 month |
| In-hospital complications from TIA or stroke | Rate of complications arising from TIA or stroke. | From admission to discharge, may be up to 1 month |
| Vital status at hospital discharge | Alive or dead | At discharge, may be up to 1 month |
| Functional status at hospital discharge | modified Rankin Scale | At discharge, may be up to 1 month |
| Neurological status at hospital discharge | National Institute of Health Stroke Scale | At discharge, may be up to 1 month |
| Cebu City |
| Philippines |
| Makati Medical Center | Makati City | Philippines |
| Jose R. Reyes Memorial Medical Center | Manila | Philippines |
| University of Santo Tomas Hospital | Manila | Philippines |
| University of the Philippines - Philippine General Hospital | Manila | Philippines |
| The Medical City | Pasig | Philippines |
| East Avenue Medical Center | Quezon City | Philippines |
| Quirino Memorial Medical Center | Quezon City | Philippines |
| St. Luke's Medical Center (QC, BGC) | Quezon City | Philippines |
| University of the East - Ramon Magsaysay Memorial Medical Center | Quezon City | Philippines |
| ID | Term |
|---|---|
| D002546 | Ischemic Attack, Transient |
| D000083242 | Ischemic Stroke |
| D002543 | Cerebral Hemorrhage |
| D013345 | Subarachnoid Hemorrhage |
| D020767 | Intracranial Thrombosis |
| ID | Term |
|---|---|
| D002545 | Brain Ischemia |
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D020521 | Stroke |
| D020300 | Intracranial Hemorrhages |
| D006470 | Hemorrhage |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D002542 | Intracranial Embolism and Thrombosis |
| D013923 | Thromboembolism |
| D016769 | Embolism and Thrombosis |
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