Objective:To assess the effect of an intervention based on including 50 g of raisins (sultanas) daily in the diet for 3 months on improving cognitive performance, cardiovascular risk factors and inflammatory markers in a population of older adults without cognitive impairment.

Methodology: Randomised two parallel-group clinical trial. Population: 80 patients between 70 and 80 years of age will be included, selected from primary care clinics in Salamanca and Zamora.

Measurements and intervention: Participants included in the study will have a baseline visit and two evaluations visits at 3 and 6 months where cognitive performance (attention, executive functions, verbal memory, working memory and language) will be assessed using a brief neuropsychological battery; quality of life, using the WHOQol- AGE and EUROQOL-5D questionnaire; blood pressure; glycaemia; body composition, using an impedancemeter; and different markers of inflammation, interleukin (IL) 6, IL-1 and tumour necrosis factor alpha (TNF); and different markers of inflammation, interleukin (IL) 6, IL-1 and tumour necrosis factor alpha (TNF-α).

Participants will be randomised using the Epidat 4.0 programme into 2 groups (control group and intervention group) with a ratio of 1:1. Both groups will be instructed to continue with their usual dietary pattern without changing their habits during the study period.

Those in the control group will not receive any amount of raisins to their usual diet. The participants in the intervention group will receive 50 g of raisins and instructions on the time of day to take it (at night). The duration of this intervention will be 3 months. The daily nutritional intake of this amount of raisins is as follows: 146 kcal; 0.25 g of fat; 34 g carbohydrates of which 34 g sugars; 1.3 g protein; 1 g fibre. The total polyphenol content of total polyphenols from 50 g of raisinas is approximately 532,5 mg (phenols explorer database).

Inclusion Criteria:

• People of both sexes aged between 70 and 80 years.
• The score on the Mini Mental State Examination (MMSE) must be greater than or equal to 24 points.
• Self-employed to attend the centre where the study is carried out.
• Signature of the informed consent form.

Exclusion Criteria:

• Coronary or cerebrovascular atherosclerotic pathology.
• Diabetes mellitus
• Grade II or higher heart failure.
• Moderate or severe chronic obstructive pulmonary disease.
• Advanced renal or hepatic disease.
• Severe mental illness.
• Oncological disease under treatment diagnosed within the last 5 years or terminal condition.
• Morbid obesity (IMC ≥ 40 kg/m2).
• Intolerance and/or allergy to any of the grape components.
• Any other circumstance at the criterion of the researchers.