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Trial was planned for 2020, but Melbourne 2020 and 2021 lockdowns hindered the study.
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Randomised crossover trial to compare early vs late walking on postprandial glycaemic response at night time.
In this crossover trial, eligible participants will be randomised to a 30-minute bout of physical activity (30 minute walk) either during the day or after an evening meal. The postprandial response to the evening meal will be analysed.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Early exercise | Placebo Comparator | Participants will exercise for 30 minutes prior to an evening meal |
|
| Late exercise | Experimental | Participants will exercise for 30 minutes after an evening meal |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Early exercise | Other | Participants will exercise for 30 minutes prior to an evening meal. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Postprandial glucose | Change in glucose incremental area under the curve (iAUC) in response to a meal challenge | Three hour glucose iAUC will be calculated at nine time points (0, 15, 30, 45, 60, 90, 120, 150 and 180 mins) after beginning consumption of the test meal. |
| Measure | Description | Time Frame |
|---|---|---|
| Postprandial insulin | Change in insulin incremental area under the curve (iAUC) in response to a meal challenge | Three hour insulin iAUC will be calculated at six time points (0, 30, 60, 90, 120 and 180 mins) after beginning consumption of the test meal. |
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Inclusion criteria
Exclusion criteria
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| ID | Term |
|---|---|
| D006943 | Hyperglycemia |
| D007333 | Insulin Resistance |
| ID | Term |
|---|---|
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
| D006946 | Hyperinsulinism |
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This is a single masking study.
| Late exercise | Other | Participants will exercise for 30 minutes after an evening meal. |
|