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| ID | Type | Description | Link |
|---|---|---|---|
| 32W7 |
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Lack of funding
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Postprandial glycaemic control is an important risk factor for the development of type 2 diabetes, cardiovascular disease and all-cause mortality.
Previous research has demonstrated that exercise performed in the postprandial state paradoxically results in a deterioration in glucose tolerance in the immediate post-exercise period (Gonzalez et a. 2013; Gonzalez and Stevenson 2013). This study aims to assess the timecourse of this post-exercise effect.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Rest | Active Comparator | Breakfast followed by a rest period prior to OGTT. |
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| Exercise-immediate | Experimental | Breakfast followed by exercise and an immediate OGTT |
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| Exercise-delay | Experimental | Breakfast followed by exercise and a delayed (1 h) OGTT. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Exercise | Behavioral | Exercise at 55% of maximum power output for 30 min. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Postprandial glucose concentration area under the curve | Blood glucose concentrations will be sampled every 15 min following an oral glucose tolerance test. | 90 min |
| Measure | Description | Time Frame |
|---|---|---|
| Postprandial insulin concentration area under the curve | Insulin concentrations will be determine every 15 min following an oral glucose tolerance test. | 90 min |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Javier T Gonzalez, PhD | Northumbria University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Northumbria University | Newcastle upon Tyne | Tyne and Wear | NE1 8ST | United Kingdom |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 24054351 | Background | Gonzalez JT, Stevenson EJ. Assessment of the post-exercise glycemic response to food: considering prior nutritional status. Nutrition. 2014 Jan;30(1):122-3. doi: 10.1016/j.nut.2013.05.015. Epub 2013 Sep 18. No abstract available. | |
| 23340006 | Background | Gonzalez JT, Veasey RC, Rumbold PL, Stevenson EJ. Breakfast and exercise contingently affect postprandial metabolism and energy balance in physically active males. Br J Nutr. 2013 Aug;110(4):721-32. doi: 10.1017/S0007114512005582. Epub 2013 Jan 29. |
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| ID | Term |
|---|---|
| D015444 | Exercise |
| C092779 | RE1-silencing transcription factor |
| ID | Term |
|---|---|
| D009043 | Motor Activity |
| D009068 | Movement |
| D009142 | Musculoskeletal Physiological Phenomena |
| D055687 | Musculoskeletal and Neural Physiological Phenomena |
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| Rest | Behavioral | Rest for 30 min |
|
| Delay | Behavioral | Delay between exercise and OGTT |
|