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This is an observertional study aimed at Study the association between the level of irisin expression and (Fibronectin Type III Domain Containing 5 (FDNC5) gene polymorphism and the presence and severity of coronary artery disease in patients with Type II DM.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Diseased | type II diabetic patients with documented coronary artery disease. | ||
| Control | type II diabetic patients without coronary artery disease. |
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| Measure | Description | Time Frame |
|---|---|---|
| Irisin level | detect the serum level of irisin hormone by ELIZA in nanogram/decilitre(ng/dl) | 6 months |
| FNDC5 Genotyping | whether homogenetic or heterogenetic | 6 months |
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Inclusion Criteria:
Exclusion Criteria:
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type II diabetic patients with and without coronary artery disease in our center in sohag university hospital.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Sohag uniersity hosoital | Sohag | Egypt |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 36732920 | Derived | Foad AM, Hafez A, Youssef W, Ahmed AE, Altaher AM. Irisin expression and FNDC5 (rs3480) gene polymorphism in type 2 diabetic patients with and without CAD. Arch Physiol Biochem. 2024 Oct;130(5):523-528. doi: 10.1080/13813455.2023.2173785. Epub 2023 Feb 2. |
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