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| ID | Type | Description | Link |
|---|---|---|---|
| 2020-A03186-33 | Other Identifier | ANSM |
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| Name | Class |
|---|---|
| Centre Hospitalier Universitaire de Saint Etienne | OTHER |
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Weakness of respiratory muscles is frequent after several days of mechanical ventilation. Thereby an acquired diaphragm weakness has been demonstrated, linked to an atrophy which may be identified by a decrease of muscle thickness in echography. This study aims to evaluate with ultrasound the variation of thickness of abdominal muscles after 7 days of mechanical ventilation.
Weakness of respiratory muscles is frequent after several days of mechanical ventilation. Thereby an acquired diaphragm weakness has been demonstrated, linked to an atrophy which may be identified by a decrease of muscle thickness in echography. Weakness of expiratory muscles is also frequent after 7 days of mechanical ventilation, however his cause is not clear: is it present at admission notably in elderly patients, or acquired on mechanical ventilation ? Ultrasound allows to measure the thickness of abdominal muscles which correlates with their strength. This study aims to evaluate with ultrasound the variation of thickness of abdominal muscles after 7 days of mechanical ventilation.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients under mechanical ventilation | Experimental | Ultrasound evaluation of the variation of thickness of abdominal muscles after 7 days of mechanical ventilation |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Ultrasound | Device | Ultrasound evaluation of the variation of thickness of abdominal muscles after 7 days of mechanical ventilation. |
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| Measure | Description | Time Frame |
|---|---|---|
| Thickness of the abdominal muscles (mm) | It is the sum of the thickness of rectus abdominal muscle + external oblique + internal oblique + transverse muscles. | Day 7 |
| Measure | Description | Time Frame |
|---|---|---|
| Thickness of the rectus abdominal muscles (mm) | Thickness of the rectus abdominal muscles (mm) by ultrasound measurement. | Day 7 |
| Thickness of the external oblique abdominal muscles (mm) | Thickness of the external oblique abdominal muscles (mm) by ultrasound measurement |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Pascal Beuret, MD | HOPITAL DE ROANNE | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Centre Hospitalier de Roanne | Roanne | 42328 | France |
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| ID | Term |
|---|---|
| D014463 | Ultrasonography |
| ID | Term |
|---|---|
| D003952 | Diagnostic Imaging |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
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| Day 7 |
| Thickness of the internal oblique abdominal muscles (mm) | Thickness of the internal oblique abdominal muscles (mm) by ultrasound measurement | Day 7 |
| Thickness of the transverse abdominal muscles (mm) | Thickness of the transverse abdominal muscles (mm) by ultrasound measurement | Day 7 |
| Diaphragmatic thickness (mm) | Diaphragmatic thickness (mm) measured by ultrasound | Day 7 |
| Diaphragmatic thickness (mm) | Diaphragmatic thickness (mm) measured by ultrasound | Immediately after the successful extubation of the patient |
| Number of day with a contraction of the transverse abdominal muscle | Ultrasound search for a contraction of the transverse abdominal muscle during the morning clinical examination each day from D1 to D7 | From day 1 to day 7 |
| Caught peak expiratory flow (CPEF) (cmH2O) | Only for conscious patients, responding to the simple command and tolerating minimal respiratory support (inspiratory support 7 cmH20, Pep 0 cmH20) caught peak expiratory flow (CPEF) measurement | Day 7 |
| Maximum expiratory pressure (l/min) | Only for conscious patients, responding to the simple command and tolerating minimal respiratory support maximum expiratory pressure (PE max) measurement | Day 7 |
| Thickness of the external oblique abdominal muscle (mm) | External oblique abdominal muscle by ultrasound measurement | Immediately after the successful extubation of the patient |
| Thickness of the internal oblique abdominal muscle (mm) | Internal oblique abdominal muscle by ultrasound measurement | Immediately after the successful extubation of the patient |
| Thickness of the transverse abdominal muscle (mm) | Transverse abdominal muscle by ultrasound measurement | Immediately after the successful extubation of the patient |
| Thickness of the rectus abdominal muscle (mm) | Rectus abdominal muscle by ultrasound measurement | Immediately after the successful extubation of the patient |
| Number of day between day 7 and successful extubation day (days) | From Day 7 to the day when the patient will be extubated successfully |
| Duration of sedation (Day) | At intensive care unit discharge |
| Duration of curarization (Day) | At intensive care unit discharge |