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Establish and verify the feasibility and effectiveness of VA-ECMO remote limb re-perfusion monitoring technology.
It is proposed to monitor VA-ECMO arterial end side branch circulation in real time through a set of monitoring equipment, guide clinical adjustment, improve lower limb re-perfusion, reduce the occurrence of lower limb ischemia, in order to achieve the goal of early detection, early prevention and early treatment, and provide reference and theoretical basis for clinical practice.
Monitoring techniques are divided into two parts: A. monitoring equipment (connecting transdiotic monitoring pressure on va-ECMO side branches cycle); B.to guide clinical adjustment by monitoring pressure (average arterial pressure).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| routine treatment | Placebo Comparator | routine nursing |
|
| Experimental group | Experimental | Immediately after the establishment of the side branch cycle, the closed transdone is connected for real-time monitoring of pressure, and clinical nursing practice is guided by transdictor pressure. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Closed transdyser | Behavioral | When the average arterial pressure ≥ 50mmHg, it is indicated that the basic blood supply of the lower extremities is satisfied without special treatment, and when the average arterial pressure < 50mmHg, it indicates insufficient perfusion, by adjusting the pipe position, changing the ECMO flow rate, and properly clamping the artery end to divert part of the blood flow to the side branch circulation, so that the average arterial pressure is maintained above 50mmHg. |
| Measure | Description | Time Frame |
|---|---|---|
| Incidence of ischemia Incidence of ischemia | of ischemia in the lower extremities on the side of the tube | 1 year |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Fei Zeng | Contact | 13757119536 | zengfei@zju.edu.cn |
| Name | Affiliation | Role |
|---|---|---|
| Fei Zeng | Second Affiliated Hospital, School of Medicine, Zhejiang University | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| SAHZhejiangU | Recruiting | Hangzhou | Zhejiang | 310000 | China |
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transdynation for real-time pressure monitoring
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| Routine monitor | Behavioral | Obtain oxygen saturation, skin color, temperature, etc |
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