Hemodynamic Comparison of Peripheral and Central VA ECMO.

Comparison of Peripheral and Central Intubation on Hemodynamics in Veno-arterial-extracorporeal Membrane Oxygenation (RECOVERY): a National, Multi-center, Prospective, Cohort Study

The goal of this clinical trial is to monitor hemodynamic differences between central veno-arterial extracorporeal membrane oxygenation (VA ECMO) and peripheral VA ECMO. The main question it aims to answer is:

• Efficacy of the different cannulation strategies for the establishment of for VA-ECMO circulation on hemodynamics and organ perfusion.

Participants require VA ECMO support, will be divided into two groups in an intention-to-treat analysis: central artery cannulation and peripheral artery cannulation.

Researchers will analyze different cannulation strategies for VA-ECMO and identify potential advantages and disadvantages for two groups of VA-ECMO.

Inclusion Criteria:

• Age≥18 years
• Participants with cardiogenic shock
• Obtaining informed consent from participants or their affiliated beneficiaries

Exclusion Criteria:

• Irreversible heart failure
• Contraindications to anticoagulation therapy
• Uncontrolled bleeding
• Irreversible neurological pathology
• Participants limited to extracorporeal cardiopulmonary resuscitation