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Since the 2000s, the incidence of bacterial STIs increases, mainly among men who have sex with men but also among heterosexual men and women with multiple sexual partners. A partner notification (PN) approach could break transmission chains and curb STI epidemics. PN brings together a set of interventions to help people diagnosed with STIs to inform their partners, encourage them to get tested, so that they can access treatment or prevention. A PN approach, systematically offered at STI diagnosis, has not yet been implemented in France and needs to be evaluated. In 2018, the Conseil National du Sida (French National AIDS Council) stated in favor of a formalized PN approach, particularly in testing centers, which carry out a large part of STI diagnoses.
The aim of our research project is to build interventions facilitating information, testing and treatment of partners of people diagnosed with STIs in testing centers and sexual health clinics.
Step 1: A cross-sectional study
Primary objective
To describe the PN practices of people diagnosed with an STI in testing centers and sexual health clinics without any intervention
Secondary objectives
Step 2: A qualitative study
Objectives
Expected results
This study is the first step in implementation of a PN program as part of a comprehensive management of STI diagnoses in France.
Methods
Step 1: A cross-sectional study
Cross-sectional study conducted in testing centers and sexual health clinics (6 centers, 6 months of enrollment), targeting two populations:
This study is based on 3 online self-administered questionnaires:
A notified partner diagnosed with an STI will receive also the questionnaire on spontaneous practices of index patients at M1. This will allow us to observe whether people who had already been notified for an STI are more likely to notify their partners.
Step 2: A qualitative study
Focus-groups of 6-8 volunteers involved in STI testing in testing centers and sexual health clinics will be conducted based on an interview guide. Doctors and other staffs will be interviewed separately.
Thematic analysis
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Index patients | People aged 18 or more diagnosed with >= 1 STI in testing centers. [STI = bacterial STIs and/or HIV and/or acute hepatitis C virus (HCV)] |
| |
| Notified partners | People aged 18 or more getting STI testing in testing centers after being notified by a sexual partner. [STI = bacterial STIs and/or HIV and/or acute HCV] |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| 2 online self-administered questionnaires on | Other |
|
|
| Measure | Description | Time Frame |
|---|---|---|
| Partner notification by index patients | Proportion of index patients who notified at least one sexual partner one month after their STI diagnosis | One month after STI diagnosis |
| Measure | Description | Time Frame |
|---|---|---|
| Partners notified by index patients | Mean proportion of notified partners among partners reported by index patients | One month after STI diagnosis |
| Notified partners tested positive | Proportion of notified partners tested positive among notified partners attending STI testing |
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Inclusion Criteria:
For index patients
For notified partners
Non-Inclusion Criteria:
For index patients and notified partners
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Two distinct populations will be studied
Index patients and notified partners will be included on a voluntary basis. The study will be offered to all eligible individuals during the study period.
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| Name | Affiliation | Role |
|---|---|---|
| Jade Ghosn, Pr | IAME, Inserm UMR1137, Paris and Infectious diseases department, Bichat Hospital, Paris | Principal Investigator |
| Karen Champenois | IAME, Inserm UMR1137, Paris | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CeGIDD d'Aix-en-Provence | Recruiting | Aix-en-Provence | France |
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| ID | Term |
|---|---|
| D012749 | Sexually Transmitted Diseases |
| D000163 | Acquired Immunodeficiency Syndrome |
| ID | Term |
|---|---|
| D003141 | Communicable Diseases |
| D007239 | Infections |
| D000091662 | Genital Diseases |
| D000091642 | Urogenital Diseases |
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| 2 online self-administered questionnaires on | Other |
|
|
| At notified partners inclusion |
| CeGIDD de Caen | Recruiting | Caen | France |
|
| CeGIDD de Lille | Recruiting | Lille | France |
|
| CeGIDD - La Joliette | Recruiting | Marseille | France |
|
| CeGIDD - Saint Adrien | Recruiting | Marseille | France |
|
| CeGIDD de Bichât | Recruiting | Paris | France |
|
| CeGIDD de La Pitié Salpêtrière | Recruiting | Paris | France |
|
| Centre de santé sexuelle - LE 190 | Recruiting | Paris | France |
|
| Institut Alfred Fournier | Recruiting | Paris | France |
|
| D020969 |
| Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D015658 | HIV Infections |
| D000086982 | Blood-Borne Infections |
| D015229 | Sexually Transmitted Diseases, Viral |
| D016180 | Lentivirus Infections |
| D012192 | Retroviridae Infections |
| D012327 | RNA Virus Infections |
| D014777 | Virus Diseases |
| D012897 | Slow Virus Diseases |
| D007153 | Immunologic Deficiency Syndromes |
| D007154 | Immune System Diseases |