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This is a 5-year cross-disciplinary sexually transmitted infection (STI) project involving a) territory-wide and community-based studies (survey and specimen collection); b) simulation of STI transmission dynamics and comparison of STI intervention strategies through mathematical modelling and cost-effectiveness analysis. The aim of this project is to assess the burden and the transmission dynamics of STIs in the general population and men who have sex with men (MSM) in Hong Kong. Around 1300 sexually experienced adults and 900 MSM would be recruited, 100 participants would be invited for individual in-depth interviews. Main outcome measures include STI history and service preference, effectiveness as measured by the proportion of new STI infections (chlamydia, gonorrhoea and human papillomavirus infections) averted above base-case scenario, and incremental cost-effectiveness ratio.
After completion of baseline questionnaire, the participants are invitied for STI self-sampling. If agree, a package of self-sampling kits, instructions, and packaging materials for return post would be delivered to their selected collection points. The second round of self-sampling would be offered at least one year from the first round of self-sampled specimens collected.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| General population | sexually experienced adults (aged 18 or above) of the randomly selected household |
| |
| men who have sex with men | men who have sex with men aged 18 or above and normally living in Hong Kong |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| self-sampling kits for STI testing in laboratory | Other | participants in both groups will receive self-sampling kits and deliver the collected samples to laboratory for testing |
|
| Measure | Description | Time Frame |
|---|---|---|
| self-reported STI diagnosis in questionnaire | number of STI diagnosis | up to 2 years |
| effectiveness of STI intervention strategies | incremental cost-effectiveness ratio | 10 years |
| Measure | Description | Time Frame |
|---|---|---|
| STI symptom reported in questionnaire | types of symptom presentations | 12 months |
| willingness to pay for STI testing reported in questionnaire | willingness to pay (HKD) |
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Inclusion Criteria:
Exclusion Criteria:
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sexually experienced adults
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| Name | Affiliation | Role |
|---|---|---|
| Ngai Sze Wong, PhD | Chinese University of Hong Kong | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| The Chinese University of Hong Kong | Hong Kong | Hong Kong, China | 0000 | Hong Kong |
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| ID | Term |
|---|---|
| D012749 | Sexually Transmitted Diseases |
| D006716 | Homosexuality |
| ID | Term |
|---|---|
| D003141 | Communicable Diseases |
| D007239 | Infections |
| D000091662 | Genital Diseases |
| D000091642 | Urogenital Diseases |
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| ID | Term |
|---|---|
| D007753 | Laboratories |
| ID | Term |
|---|---|
| D000072182 | Non-Medical Public and Private Facilities |
| D006268 | Health Facilities |
| D005159 | Health Care Facilities Workforce and Services |
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urine, penile swab, cervical swab, rectal swab, pharyngeal swab
| 12 months |
| prevalence of STI estimated through laboratory testing | prevalence of chlamydia trachomatis, Neisseria gonorrhoeae and human papillomavirus infections from self-collected samples | 12 months |
| D020969 |
| Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D019529 | Sexuality |
| D012725 | Sexual Behavior |
| D001519 | Behavior |