Universal Genetic Testing Versus Guidelines-Directed Testing for Germline Pathogenic Variants Among Non-Western Patients With Breast Cancer

Universal Genetic Testing Versus Guidelines-Directed Testing for Germline Pathogenic Variants Among Non-Western Patients With Breast Cancer

The study aims to examinethe pattern and frequency of pathogenic variants among all newly diagnosed breast cancer patients in a genetically distinct population. Additionally, the uptake rate of "cascade family screening" , frequency of pathogenic variants and barriers against testing will be studied.

Inclusion Criteria:

• Adult patient, age ≥ 18 years at time of cancer diagnosis
• Pathology proven diagnosis of breast cancer (including DCIS); any stage. (prior history of cancer is allowed)
• Willingness to participate
• Signed consent form.

Exclusion Criteria:

- Major psychiatric disorder (defined as: patients followed by a psychiatrist and on antipsychotic medications