The investigators aim to study the pattern and frequency of pathogenic variants among ALL newly diagnosed cancer patients in a genetically distinct population.

Additionally, the investigators will study the uptake rate of "cascade family screening", frequency of pathogenic variants and barriers against testing.

Inclusion Criteria:

• Adult patient, age ≥ 18 years at time of cancer diagnosis
• Pathology proven diagnosis of cancer; any site, any stage (prior history of cancer is allowed)
• Jordanian nationality
• Willingness to participate
• Signed consent form

Exclusion Criteria:

• Major psychiatric disorder (defined as: patients followed by a psychiatrist and on antipsychotic medications)
• Non-Jordanian
• Patients with Leukemia, Lymphoma and Myeloma

All consecutive patients who fulfill the inclusion/exclusion criteria and are diagnosedat KHCC will be invited.

A total of 3000 patients are estimated to participate