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The main objectives are to determine the validity of a Smart Cap in measuring fluid intake during running and fitness exercise and the validity of a Smart Sweat Patch in measuring sweat rate and sweat chloride concentration during outdoor cycling, running, and fitness exercise. A secondary objective is to compare regional sweating rate and sweat electrolyte concentrations (sodium, chloride, and potassium) on contralateral arms with vs. without tattoos.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Smart sweat patch for sweat rate and sweat chloride concentration | Experimental | Epidermal microfluidic patch that is a flexible 27 cm2 platform with an adhesive backing that collects sweat through a skin-facing inlet port. Custom software uses the smartphone camera to capture and analyze the microfluidic patch. |
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| Reference sweat patch for sweat rate and sweat electrolytes | Placebo Comparator | Regional absorbent patch technique for sweat rate (gravimetry) and electrolytes (sodium, potassium, chloride) by ion chromatography |
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| Smart Cap bottle fluid measurement | Experimental | Fluid level sensor integrated into the squeeze bottle cap measures the amount of fluid remaining in the bottle via light reflection |
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| Reference method bottle fluid measurement | Other | Scale weight of bottle (gravimetry method) for Smart Cap bottles (running and fitness subjects) and non-Smart Cap bottles (cyclists) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Smart Cap, running and fitness exercisers only | Device | Bottle cap |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Fluid intake | Smart Cap (sensor) versus Reference method (bottle weight) | Change from baseline to up to 1 hour of exercise |
| Regional sweating rate | Sweat Patch versus Reference patch method | Change from baseline to up to 2 hours of exercise |
| Regional sweat chloride concentration | Sweat Patch versus Reference patch method | Change from baseline to up to 2 hours of exercise |
| Measure | Description | Time Frame |
|---|---|---|
| Regional sweating rate with versus without tattoos | Reference sweat patch method | Change from baseline to up to 2 hours of exercise |
| Regional sweat sodium and potassium with versus without tattoos |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Lindsay Baker, PhD | PepsiCo Global R&D, Gatorade Sports Science Institute (GSSI) | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Gatorade Sports Science Institute (GSSI), 617 West Main Street | Barrington | Illinois | 60010 | United States | ||
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 38821996 | Derived | Merritt JR, Ozga M, De Chavez PJD, Boolani A, Baker LB. No effect of tattoos on local sweat concentrations of select cytokines, cortisol, glucose, blood urea nitrogen, or lactate during exercise. Sci Rep. 2024 May 31;14(1):12570. doi: 10.1038/s41598-024-63057-0. | |
| 35778519 | Derived | Keyes DM, Brown SD, King MA, Engel MD, Ciciora-Gold M, Chavez PJD, Baker LB. Multiple regression analyses to determine the effect of sweating rate and tattoo characteristics on sweat outcome measures during exercise. Eur J Appl Physiol. 2022 Oct;122(10):2163-2174. doi: 10.1007/s00421-022-04989-1. Epub 2022 Jul 1. |
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Each subject will serve as his or her own control. We will compare the Test and Reference methods during moderate intensity self-paced training runs, coach-led fitness sessions, and/or group outdoor cycling rides.
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| Sweat Patch, all subjects- running, fitness, cycling |
| Device |
Regional contralateral forearm patch |
|
| Reference sweat patch, all subjects - running, fitness, cycling | Device | Regional contralateral forearm patch |
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| Bottle Scale, all subjects - running, fitness, cycling | Other | Bottle weight |
|
Reference sweat patch method
| Change from baseline to up to 2 hours of exercise |
| Whole body sweat rate | Scale weight | Body mass change from baseline to up to 2 hours of exercise |
| Grant Park, 337 E Randolph St |
| Chicago |
| Illinois |
| 60601 |
| United States |
| Cuba Marsh Forest Preserve, 24205 Cuba Rd | Deer Park | Illinois | 60010 | United States |
| ID | Term |
|---|---|
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D001519 | Behavior |
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