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To determine the validity of a prototype patch in measuring sweating rate and sweat electrolyte concentration during moderate intensity exercise against well-established reference methods in a controlled laboratory and in field conditions.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Study Session 1 | Other | Arm Type: Validation. Regional sweat collection with prototype vs. reference patch in the laboratory |
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| Study Session 2 (repeat of Study Session 1) | Other | Arm Type: Validation: Regional sweat collection with prototype vs. reference patch in the laboratory |
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| Study Session 3 | Other | Arm Type: Validation. Prototype patch vs. whole body sweat collection in the laboratory |
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| Study Session 4 (repeat of Study Session 3) | Other | Arm Type: Validation. Prototype patch vs. whole body sweat collection in the laboratory |
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| Study Session 5 | Other | Arm Type: Validation. Regional sweat collection with prototype vs. reference patch in the field |
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| Study Session 6 (repeat of Study Session 5) |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Sweat patch | Other | Flexible, epidermal, wearable skin patch to collect and analyze sweat |
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| Measure | Description | Time Frame |
|---|---|---|
| Sweat chloride concentration | Prototype vs. reference method (regional absorbent patch technique) during exercise | 1.5 hours in sessions 1-6 |
| Measure | Description | Time Frame |
|---|---|---|
| Regional sweating rate | Prototype vs. reference method (gravimetry using the regional absorbent patch technique) during exercise | 1.5 hours in sessions 1-6 |
| Whole body sweating rate | Prototype vs. reference method (changes in nude body mass corrected for fluid intake, urine output, respiratory water loss, and metabolic mass loss) during exercise |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Lindsay B Baker, PhD | PepsiCo Global R&D, Gatorade Sports Science Institute (GSSI) PI for Barrington site | Principal Investigator |
| Khalil Lee, PhD | PepsiCo Global R&D, Gatorade Sports Science Institute (GSSI) PI for Bradenton site | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Gatorade Sports Science Institute at IMG Academy | Bradenton | Florida | 34210 | United States | ||
| Gatorade Sports Science Institute (GSSI) |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 37005963 | Derived | King MA, Brown SD, Barnes KA, De Chavez PJD, Baker LB. Regional and time course differences in sweat cortisol, glucose, and select cytokine concentrations during exercise. Eur J Appl Physiol. 2023 Aug;123(8):1727-1738. doi: 10.1007/s00421-023-05187-3. Epub 2023 Apr 2. |
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Each subject subject serves as their own control at each testing session. The prototype patch and reference method are both worn during each session.
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Arm Type: Validation. Regional sweat collection with prototype vs. reference patch in the field |
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| 1.5 hours in sessions 1-6 |
| Whole body sweat chloride concentration | Prototype vs. reference method (whole body washdown technique) during exercise | 1.5 hours in sessions 3-4 |
| Whole body sweat sodium concentration | Reference method only. Compare whole body sweat chloride concentration vs. whole body sweat sodium concentration during exercise | 1.5 hours in sessions 3-4 |
| Self-ratings of perceived sweating vs. measured sweating rate | Multiple choice questionnaire vs. sweat patch analysis | Prior to the start of exercise at sessions 1-6 |
| Self-ratings of perceived sweat saltiness vs. sweat electrolyte concentrations | Multiple choice questionnaire vs. sweat patch analysis | Prior to the start of exercise at sessions 1-6 |
| History of exercise-associated muscle cramps | Multiple choice questionnaire | Prior to the start of exercise at sessions 1-6 |
| Barrington |
| Illinois |
| 60010 |
| United States |