Anatomopathological classifications have been well identified in aortic dissection with important therapeutic implications. The authors evaluated the inflammatory response in patients with aortic dissection (AD) and assessed the presence of distinct inflammatory subphenotypes within this disease.

Inclusion Criteria:

• acute type Aortic dissection;

Exclusion Criteria:

• Iatrogenic aortic dissection OR traumatic aortic dissection
• Patients with hematological diseases, infectious diseases, malignant tumors, immune system diseases, or severe liver diseases.
• Preoperative use of mechanical ventilation, blood transfusion, renal replacement therapy, extracorporeal membrane oxygenation, or intra-aortic balloon pump during the current admission.

Patients underwent venipuncture during primary evaluation in the Emergency Department. Venous blood samples were immediately sent to the laboratory for analysis.