Not provided
Not provided
Not provided
Not provided
Not provided
financial protocol
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The aim of this study is to investigate the effect of opioid-free anesthesia using dexmedetomidine and lidocaine instead of remifentanil infusion, on the acute postoperative pain after the gynecological laparoscopy
This study is performed to investigate the effect of dexmedetomidine and lidocaine the postopeative pain, shivering, nausea and vomiting after the gynecological laparoscopy.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| dexmedetomidine-lidocaine | Experimental | The study group receives the dexmedetomidine and lidocaine infusion with general anesthesia for gynecological laparoscopy. |
|
| remifentanil | Active Comparator | The control group receives the remifentanil infusion with general anesthesia for gynecological laparoscopy |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Dexmedetomidine Hydrochloride | Drug | dexmedetomidine iv bolus for 10 minutes followed by the infusion of 0.1-1 ug/kg/h during general anesthesia |
|
| Measure | Description | Time Frame |
|---|---|---|
| postoperative pain in recovery room | The pain level is assessed by using NRS (numeric rating scale; 0=no pain , 10=the worst pain) | 30 minuetes after the completion of surgery |
| Measure | Description | Time Frame |
|---|---|---|
| shivering in recovery room | The incidence of shivering is assessed by questioning Yes or No. | 30 minuetes after the completion of surgery |
| postoperative nausea and vomiting (PONV) | The incidence of PONV is assessed by questioning Yes or No |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Young Eun Moon, MD, PhD | Associate professor, Department of Anesthesiology and Pain Medicine | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Seoul St.Mary's Hospital | Seoul | Seocho-gu | 06591 | South Korea | ||
| Seoul St.Mary's Hospital |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D005831 | Genital Diseases, Female |
| ID | Term |
|---|---|
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D000091662 | Genital Diseases |
Not provided
Not provided
| ID | Term |
|---|---|
| D020927 | Dexmedetomidine |
| D000077208 | Remifentanil |
| D008012 | Lidocaine |
| ID | Term |
|---|---|
| D007093 | Imidazoles |
| D001393 | Azoles |
| D006573 | Heterocyclic Compounds, 1-Ring |
| D006571 | Heterocyclic Compounds |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
|
| Remifentanil Hydrochloride | Drug | remifentanil iv infusion of 0.5-5 ng/ml (effect site concentration using TCI) during general anesthesia |
|
|
| Lidocaine Hydrochloride | Drug | lidocaine iv bolus followed by the infusion of 1.5mg/kg/h during general anesthesia |
|
|
| 30 minutes after the completion of surgery |
| Seocho |
| 06591 |
| South Korea |
| D011422 |
| Propionates |
| D000144 | Acids, Acyclic |
| D002264 | Carboxylic Acids |
| D009930 | Organic Chemicals |
| D010880 | Piperidines |
| D000083 | Acetanilides |
| D000813 | Anilides |
| D000577 | Amides |
| D000814 | Aniline Compounds |
| D000588 | Amines |